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Proteus Structure Prediction Server
Comprehensive Secondary Structure Predictions
 
 
 
Proteus prediction (ID=3634941) complete
Summary:
 
  • Time of Submission: 22:28:56 Apr 01, 2006
  • Sequence Name: 1ONF:A|PDBID|CHAIN|SEQUENCE
  • Number of residues read in: 500
  • Number of useable PDB homologs found: 16
    • 1ONFA, e-value = 0.0 CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM GLUTATHIONE
    • 1GERA, e-value = 5.0E-97 D GLUTATHIONE REDUCTASE (E.C.1.6.4.2) COMPLEXED WITH FAD
    • 1BWCA, e-value = 5.0E-95 STRUCTURE OF HUMAN GLUTATHIONE REDUCTASE COMPLEXED WITH
    • 1ZDLA, e-value = 4.0E-71 CRYSTAL STRUCTURE OF MOUSE THIOREDOXIN REDUCTASE TYPE 2
    • 1AOGA, e-value = 2.0E-66 TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE (OXIDIZED FORM)
    • 1H6VA, e-value = 8.0E-66 MAMMALIAN THIOREDOXIN REDUCTASE
    • 1FEAA, e-value = 5.0E-62 UNLIGANDED CRITHIDIA FASCICULATA TRYPANOTHIONE REDUCTASE AT
    • 3LADA, e-value = 1.0E-44 D DIHYDROLIPOAMIDE DEHYDROGENASE (E.C.1.8.1.4)
    • 1LPFA, e-value = 7.0E-43 D 2 FLAVIN-ADENINE-DINUCLEOTIDE (FAD)
    • 1EBDA, e-value = 8.0E-42 DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING
    • 1JEHA, e-value = 6.0E-37 CRYSTAL STRUCTURE OF YEAST E3, LIPOAMIDE DEHYDROGENASE
    • 1DXLA, e-value = 7.0E-36 DIHYDROLIPOAMIDE DEHYDROGENASE OF GLYCINE DECARBOXYLASE
    • 1ZMCA, e-value = 2.0E-32 CRYSTAL STRUCTURE OF HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE
    • 2A8XA, e-value = 1.0E-30 CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM
    • 1ZK7A, e-value = 9.0E-30 CRYSTAL STRUCTURE OF TN501 MERA
    • 1XDIA, e-value = 6.0E-18 CRYSTAL STRUCTURE OF LPDA (RV3303C) FROM MYCOBACTERIUM
  • Number of sequence alignments used for ab-initio predictions: 49
  • Overall confidence value: 88.8%
  • Predicted % Helix content: 33 % (166 residues)
  • Predicted % Beta sheet content: 31 % (157 residues)
  • Predicted % Coil content: 35 % (177 residues)
Graphical Alignment of PDB Homologs:

Conserved Domains
Legend:
  H = Helix
E = Beta Strand
C = Coil
Line 1 = sequence (single letter IUPAC code, 60 characters per line)
Line 2 = secondary structure (H, E or C)
Line 3 = confidence score (0-9, 0 = low, 9 = high)

A '*' character above the overall prediction indicates the homolog's structure was used at this residue.

Predicted Secondary Structure:
 
   1   *********************************************************** 60
      MVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDI
     
CCEEEEEECCCCHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
      999999999999999999999999999999999999999999999999999999999999

  61  ************************************************************ 120
      LENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRIL
     
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCEEEE
      999999999999999999999999999999999999999999999999999999887777

 121  ************************************************************ 180
      IKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIG
     
EEECCCCCCCCEEEEEEEEEEEEEEEEEEEEEEECCCCCCCCCEEECHHHHCCCCCEEEE
      997677888887787778889999999999999999999999999999999999999999

 181  ************************************************************ 240
      IVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADV
     
EECCCHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEEEE
      999999999999999999999999999999999999999999999999999999999999

 241  ************************************************************ 300
      VEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLNVETNNNYIVVDENQ
     
EEEEECCCCEEEEEECCCEEEEEEEEEEEECCEEEECCCCCCCCCCEEECCCEEEEECCC
      999999999999999999999999999999999999999999999999999999999999

 301  *********************************************  ************* 360
      RTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINA
     
CCCCCCEEEECCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHH
      999999999999999997377777888799999999999998777779999999999999

 361  ************************************************************ 420
      GRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYESKFTNL
     
HHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHCCCEEEEEEEEEECC
      999999999999999999999999999999999999999999999999999999999999

 421  ************************************************************ 480
      FFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATKKDFDE
     
CCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHH
      999999999999999999999999999999999999999999999999999999999999

 481  ******************** 500
      TIPIHPTAAEEFLTLQPWMK
     
CCCCCCCCHHHCCCCCCCCC
      99999999999999998889



    Proteus uses a "Jury of Experts" approach involving predictions from PSIPRED ( Jones, 1999 ), JNET ( Barton et al., 1999 ), TRANSSEC (a locally developed tool), and structural alignment ( XALIGN ). Following is the predicted secondary structure from each component.
Detailed Prediction Information:
 

PSIPRED
   1  MVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDI 60
     
CCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCHHHHCHHHHHHH
      965699998998999999999987997999988988877888677776455445778999

  61  LENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRIL 120
     
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCEEE
      986676687765554699999999999999999999999869858999999998585999

 121  IKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIG 180
     
EEECCCCCCEEECCCCCEEEEECEEEEECCCEEEECCCCCHHHHCCCHHHHHHHCCCEEE
      986677655455578875998788999689865558899855654657887665789799

 181  IVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADV 240
     
EECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHCCCEEEECCEE
      996888999999999987996999976884455656999999999999789999989899

 241  VEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLNVETNNNYIVVDENQ 300
     
EEEEECCCCEEEEEECCCEEEEEEEEEEEEECEEECHHHCCCCCCCEEECCCEEEECCCC
      999996898999999799588776799998575546665466777678779978989846

 301  RTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINA 360
     
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
      679998599876346766544455667889999998765655455556788765899999

 361  GRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYESKFTNL 420
     
HHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEECCHHHHHHHCCCCCEEEEEECCCCC
      999999985998766788866899996645788868999999965988669998657877

 421  FFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATKKDFDE 480
     
CCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHH
      665555444689985899999999999999999869989999999999988999999984

 481  TIPIHPTAAEEFLTLQPWMK 500
     
HCCCCCCCHHHHHHHCCCCC
      46778884676886556679



JNET
   1  MVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDI 60
     
CCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
      636168871785147889999870784588871888642686143567012334688899

  61  LENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRIL 120
     
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCEEE
      987358887645310489999998888876421156654118817887235674575478

 121  IKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIG 180
     
EEECCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEE
      871688734775068860553013677558876789998752101102455307999278

 181  IVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADV 240
     
EECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCE
      870460456789998864994688762887756650678888888887489968863513

 241  VEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLNVETNNNYIVVDENQ 300
     
EEEEECCCCEEEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHCCCCCEEEEECCC
      688865885688887278532212356777314167211133232111288728874145

 301  RTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINA 360
     
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
      667994488603655553123456789999989999998776533436676315888888

 361  GRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYESKFTNL 420
     
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCCHHHHHHHHCCCCCEEEEEECCCCC
      999999982788776788762068883442121365268887761886178874137841

 421  FFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATKKDFDE 480
     
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHC
      111001233799853478888579963678887358862789999999862675466512

 481  TIPIHPTAAEEFLTLQPWMK 500
     
CCCCCCCCHHHHHHHCCCCC
      33556775467764189899



TRANSSEC
   1  MVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDI 60
     
CCCEEEEECCCCCCHHHHHHHHHHCEEEEEEECCCCCEEEEEEEECCCCEEEEEEEEEEE
      987899985799866788777766979999996778968999876576446777778776

  61  LENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRIL 120
     
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCEEEECCCCE
      568767898766665457788877777766555445546655689998575788655668

 121  IKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIG 180
     
EEEEECCCCCEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECHHHHHCCCCEEE
      999776898654677889899999999976776787678754676555456645687699

 181  IVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADV 240
     
EECCCCEEEECHHHHHHCCEEEEEEEECHHHHCCCCCHHHHHHHHHHHCCEEEEEEEEEE
      976875565555577748847898887535447887557899888654468988667899

 241  VEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLNVETNNNYIVVDENQ 300
     
EEEEECCCCCEEECCEEEECCCCEEEEEEEECCCCCCCCEEEEEEEEEECCCEEEEEEEC
      999876899789966876688988999999858888775445678888758899999865

 301  RTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINA 360
     
CCEEEEEEEECCCEEEEEEEEEEEEEEEEEEEEEEEEECCCCCEEECCCCCEEEHHHHHH
      885678999867545778899999999999999999988898777656774455567655

 361  GRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYESKFTNL 420
     
HHHHCEEEEECCCCEEEEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEE
      466545565368865665678889875777656655777777766997589999998665

 421  FFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATKKDFDE 480
     
EECCCCCCCCCCCCEEEEEEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEE
      445776544577766799995866885889999865877789999998765674566655

 481  TIPIHPTAAEEFLTLQPWMK 500
     
EEECCCCCCHHHHHHCCCCC
      56658887557886468889



JURY-OF-EXPERTS PREDICTION
   1  MVYDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDI 60
     
CEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
      969999975896799999999984868999985899869998667777688889999999

  61  LENSRHYGFDTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLSENRIL 120
     
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEECCCEEE
      998765788888876489999999999999999999999866699999999997797689

 121  IKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKGIENTISSDEFFNIKESKKIG 180
     
EEECCCCCEEEECCCCEEEEEEEEEEEECCCCEEECCCCCHHHCCCHHHHHHHCCCEEEE
      999689875787689958999899999867767756777645446747889865896999

 181  IVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADV 240
     
EEECCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEECCEE
      964877899999999885879999996776455687899999999999865999977778

 241  VEIKKVSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLNVETNNNYIVVDENQ 300
     
EEEEECCCCEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCEEEEEECCC
      999967997799997578766889999999655567766565544668768699995678

 301  RTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINA 360
     
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
      887758998876567776378999999999999999999998646556888755999999

 361  GRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKENVKIYESKFTNL 420
     
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCEEEECCCHHHHHHHCCCCEEEEEEEECCCC
      999999998477877766658999998566567656589999975897899999957775

 421  FFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVALKMNATKKDFDE 480
     
CCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHH
      567777766788868999999879988999999769959999999999996553799986

 481  TIPIHPTAAEEFLTLQPWMK 500
     
HCCCCCCCHHHHHHHCCCCC
      45888986799988768889

3D-TO-2D MAPPING FOR TOP-SCORING HOMOLOG:

QUERY MVYDLIVIGGGSGGMAAARRAAR-HN---AKVALVE---------K---------S---- 34
1ONFA ~VYDLIVIGGGSGGMAAARRAAR-HN---AKVALVE---------K---------S----
      ~CEEEEEECCCCHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
1GERA ~~YDYIAIGGGSGGIASINRAAM-YG---QKCALIE---------A---------K----
      ~~EEEEEECCHHHHHHHHHHHHH~CC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
1BWCA ~~YDYLVIGGGSGGLASARRAAE-LG---ARAAVVE---------S---------H----
      ~~EEEEEECCCHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~E~~~~
1ZDLA ~~FDLLVIGGGSGGLACAKEAAQ-LG---KKVAVADYVEPSPRGTK---------W----
      ~~EEEEEECCCHHHHHHHHHHHH~HC~~~EEEEEEEECCCCCCCCC~~~~~~~~~C~~~~
1AOGA ~IFDLVVIGAGSGGLEAAWNAATLYK---KRVAVID---------VQMVHGPPFFS----
      ~EEEEEEECCCHHHHHHHHHHHHCCC~~~EEEEEEE~~~~~~~~~CCCCCCCCCCC~~~~
1H6VA ~~FDLIIIGGGSGGLAAAKEAAK-FD---KKVMVLDFVTPTPLGTN---------W----
      ~~EEEEEECCHHHHHHHHHHHHH~HC~~~EEEEEEEECCCCCCCCC~~~~~~~~~E~~~~
1FEAA ~~YDLVVIGAGSGGLEAGWNAASLHK---KRVAVID---------L---------Q----
      ~~EEEEEECCCCHHHHHHHHHHHCCC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
3LADA ~~FDVIVIGAGPGGYVAAIKSAQ-LG---LKTALIE---------K---------Y----
      ~~EEEEEECCCHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~E~~~~~~~~~E~~~~
1LPFA ~~FDVVVIGAGPGGYVAAIRAAQ-LG---LKTACIE---------K---------YIGKE
      ~~EEEEEECCHHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~E~~~~~~~~~CCCCC
1EBDA ~~~ETLVVGAGPGGYVAAIRAAQ-LG---QKVTIVE---------K---------G----
      ~~~EEEEECCHHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
1JEHA ~~HDVVIIGGGPAGYVAAIKAAQ-LG---FNTACVE---------KR--------G----
      ~~EEEEEECCHHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~CC~~~~~~~~C~~~~
1DXLA ~~~DVVIIGGGPGGYVAAIKAAQ-LG---FKTTCIE---------KR--------G----
      ~~~EEEEECCCHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~CC~~~~~~~~C~~~~
1ZMCA ~~~DVTVIGSGPGGYVAAIKAAQ-LG---FKTVCIE---------K---------N----
      ~~~EEEEECCHHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
2A8XA ~~YDVVVLGAGPGGYVAAIRAAQ-LG---LSTAIVE---------P---------K----
      ~~EEEEEECCHHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
1ZK7A ~~~~~~VIGSGGAAMAAALKAVE-QG---AQVTLIE---------R---------G----
      ~~~~~~EECCHHHHHHHHHHHHH~HC~~~EEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~
1XDIA ~~~~IVILGGGPAGYEAALVAAT-SHPETTQVTVID---------C---------D----
      ~~~~EEEECCCHHHHCHHHHHHH~HCCCEEEEEEEE~~~~~~~~~C~~~~~~~~~C~~~~


  34  ---R---------LGGTCVNVGCVPKK-IMFNAA-SV-HDILE-NSRHYGF--D---T-- 71
1ONFA ---R---------LGGTCVNVGCVPKK-IMFNAA-SV-HDILE-NSRHYGF--D---T--
      ~~~C~~~~~~~~~CCCCCCCCCCHHHH~HHHHHH~HH~HHHHH~CHHHCCC~~C~~~C~~
1GERA ---E---------LGGTCVNVGCVPKK-VMWHAA-QI-REAIHMYGPDYGF--D---T--
      ~~~C~~~~~~~~~CCCCCCCCCHHHHH~HHHHHH~HH~HHHHHHHHHHHCC~~C~~~C~~
1BWCA ---K---------LGGTCVNVGCVPKK-VMWNTA-VH-SEFMH-DHADYGF--P---SC-
      ~~~E~~~~~~~~~ECCCCCCCCHHHHH~HHHHHH~HH~HHHHH~HHCCCCC~~C~~~CC~
1ZDLA ---G---------LGGTCVNVGCIPKK-LMHQAA-LL-GGMIR-DAHHYGW--E---VAQ
      ~~~C~~~~~~~~~CCCEEECCCCHHHH~HHHHHH~HH~HHHHH~HHHCCCC~~C~~~CCC
1AOGA ---A---------LGGTCVNVGCVPKK-LMVTGA-QY-MEHLR-ESAGFGW--EFDRT--
      ~~~C~~~~~~~~~CCCCCCCCCHHHHH~HHHHHH~HH~HHHHH~HHHHCCC~~CCCCC~~
1H6VA ---G---------LGGTCVNVGCIPKK-LMHQAA-LL-GQALK-DSRNYGWKLE---D--
      ~~~E~~~~~~~~~ECCCCCCCCHHHHH~HHHHHH~HH~HHHHH~HHHHHCCCCC~~~C~~
1FEAA ---KHHGPPHYAALGGTCVNVGCVPKK-LMVTGA-NY-MDTIR-ESAGFGW--ELDRE--
      ~~~CCCCCCCCCCCCCCCCCCCHHHHH~HHHHHH~HH~HHHHH~HHHCCCC~~CCCCC~~
3LADA ---KGKEGKTA--LGGTCLNVGCIPSK-ALLDSSYKF-HEAHE-SFKLHGI--S---TG-
      ~~~CCCCCCEE~~ECCCCCCCCCHHHH~HHHHHHHHH~HHHHC~CCCCCCC~~C~~~CC~
1LPFA GKVA---------LGGTCLNVGCIPSK-ALLDSSYKY-HEAKE-AFKVHGI--E---A--
      CCEE~~~~~~~~~ECCHHHHCCHHHHH~HHHHHHHHH~HHHHH~CCCCCCC~~C~~~C~~
1EBDA ---N---------LGGVCLNVGCIPSK-ALISAS-HR-YEQAK-HSEEMGI--K---A--
      ~~~C~~~~~~~~~CCCCCCCCCCHHHH~HHHHHH~HH~HHHHH~CCCCCCC~~C~~~C~~
1JEHA ---K---------LGGTCLNVGCIPSK-ALLNNS-HLFHQMHT-EAQKRGI--D---V--
      ~~~C~~~~~~~~~CCCCCCCCCHHHHH~HHHHHH~HHHHHHHH~HHHCCCC~~C~~~C~~
1DXLA ---A---------LGGTCLNVGCIPSK-ALLHSS-HMYHEAKH-SFANHGV--KV--S--
      ~~~C~~~~~~~~~CCCEEECCCCCHHH~HHHHHH~HHHHHHHH~HCCCCCC~~CC~~C~~
1ZMCA ---ET--------LGGTCLNVGCIPSK-ALLNNS-HY-YHMAH-GTDFASR--G---I--
      ~~~CC~~~~~~~~CCCHHHHCCHHHHH~HHHHHH~HH~HHHHH~CHHHHHH~~C~~~C~~
2A8XA ---Y---------WGGVCLNVGCIPSKALLRNAE-LV-HIFTK-DAKAFGI--S---G--
      ~~~C~~~~~~~~~CCCCCCCCCCHHHHHHHHHHH~HH~HHHHH~CCCCCCC~~C~~~C~~
1ZK7A ---T---------IGGTCVNVGCVPSK-IMIRAA-HI-AHL----RRESPF--D---G--
      ~~~C~~~~~~~~~CCCHHHHCCHHHHH~HHHHHH~HH~HHH~~~~HHCCCC~~C~~~C~~
1XDIA ---G---------IGGAAVLDDCVPSK-TFIAST-GL-RTELR-RAPHLGF--H------
      ~~~C~~~~~~~~~CCCCCCCCHHHHHH~HHHHHH~HH~HHHCC~CHHHHCC~~C~~~~~~


  72  K--FS---FNLPL-----LVERRDKYIQ-RLNNIYRQNL--S-KDKVDLYEGTASFLSEN 117
1ONFA K--FS---FNLPL-----LVERRDKYIQ-RLNNIYRQNL--S-KDKVDLYEGTASFL---
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~CCCEEEEEEECEEE~~~
1GERA T--INK--FNWET-----LIASRTAYID-RIHTSYENVL--G-KNNVDVIKGFARFVDAK
      C~~CCC~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEECCCE
1BWCA E--GK---FNWRV-----IKEKRDAYVS-RLNAIYQNNL--T-KSHIEIIRGHAAFTSDP
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEECEEEEECCC
1ZDLA P--VQ---HNWKT-----MAEAVQNHVK-SLNWGHRVQL--Q-DRKVKYFNIKASFVDEH
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHCHHHHH~~H~CCCEEEEEEEEEECCCC
1AOGA T--LR---AEWKN-----LIAVKDEAVL-NINKSYDEMFR-D-TEGLEFFLGWGSLESKN
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHHH~H~CCCEEEEECEEEECCCE
1H6VA T--VK---HDWEK-----MTESVQNHIG-SLNWGYRVAL--R-EKKVVYENAYGKFIGPH
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEECCCC
1FEAA S--VR---PNWKA-----LIAAKNKAVS-GINDSYEGMF--ADTEGLTFHQGFGALQDNH
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~HCCCCEEEEECEEEECCCE
3LADA E--VA---IDVPT-----MIARKDQIVR-NLTGGVASLI--K-ANGVTLFEGHGKLLAGK
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEEECCC
1LPFA KG-VT---IDVPA-----MVARKANIVK-NLTGGIATLF--K-ANGVTSFEGHGKLLANK
      CC~CC~~~CHHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEEECCC
1EBDA EN-VT---IDFAK-----VQEWKASVVK-KLTGGVEGLL--K-GNKVEIVKGEAYFVDAN
      CC~CC~~~CHHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HCCEEEEEEEEEECCCE
1JEHA NGDIK---INVAN-----FQKAKDDAVK-QLTGGIELLF--K-KNKVTYYKGNGSFEDET
      CCCCC~~~CHHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEECCCC
1DXLA N--VE---IDLAA-----MMGQKDKAVS-NLTRGIEGLF--K-KNKVTYVKGYGKFVSPS
      C~~CC~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEECCCE
1ZMCA E--MSEVRLNLDK-----MMEQKSTAVK-ALTGGIAHLF--K-QNKVVHVNGYGKITGKN
      C~~CCCCCCHHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEECCCE
2A8XA E--VT---FDYGI-----AYDRSRKVAEGRVAGVH--FL--K-KNKITEIHGYGTFADAN
      C~~CC~~~CCHHH~~~~~HHHHHHHHHHHHHHHHH~~HC~~C~CCCEEEEEEEEEECCCE
1ZK7A G--IA---ATVPTIDRSKLLAQQQARVD-ELRHAKYEGILGG-NPAITVVHGEARFKDDQ
      C~~CC~~~EEECCCCHHHHHHHHHHHHH~HHHHHHCHHHHCC~CCCEEEEEEEEEECCCE
1XDIA ----K---ISLPQ-----IHARVKTLAA-AQSADITAQL--L-SMGVQVIAGRGELIDST
      ~~~~C~~~CCHHH~~~~~HHHHHHHHHH~HHHHHHHHHH~~H~HHCEEEEEEEEEEECCC


 118  RILIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKP-V-FP---PVKG-I-E----NT-- 164
1ONFA -----------------------EGRNILIAVGNKP-V-FP---PVKG-I-E----NT--
      ~~~~~~~~~~~~~~~~~~~~~~~CEEEEEEEECEEE~E~CC~~~CCCC~C~C~~~~CE~~
1GERA TLEVNG--------------ETITADHILIATGGRP-S-HP---DIPG-V-E----YG--
      EEEECC~~~~~~~~~~~~~~CEEEEEEEEEECCEEE~E~CC~~~CCCC~C~C~~~~CE~~
1BWCA KPTIEVS---GKKYTAP---------HILIATGGMP-S-TPHESQIPG-A-S----LG--
      CEEEEEC~~~CEEEEEC~~~~~~~~~EEEEECCEEE~E~CCCHHHCCC~C~C~~~~CE~~
1ZDLA TV--------RGVDKGG-KATLLSAEHIVIATGGRP-R-YPT--QVKGAL-E----YG--
      EE~~~~~~~~EEEECCC~EEEEEEEEEEEEECCEEE~E~CCC~~CCCCCC~C~~~~CE~~
1AOGA VVNVR-----ESADPASAVKERLETEHILLASGSWP-H-MP---NIPG-I-E----HC--
      EEEEE~~~~~ECCCCCEEEEEEEEEEEEEEECCEEE~E~CC~~~CCCC~C~C~~~~CE~~
1H6VA KIMA-----TNNKG----KEKVYSAERFLIATGERP-R-YL---GIPGDK-E----YC--
      EEEE~~~~~ECCCC~~~~EEEEEEEEEEEEECCEEE~E~CC~~~CCCCCC~C~~~~CE~~
1FEAA TVLVRESADPNS-----AVLETLDTEYILLATGSWP-Q-HL---GIEG-D-D----LC--
      EEEEEECCCCCE~~~~~EEEEEEEEEEEEEECCEEE~E~CC~~~CCCC~C~C~~~~CE~~
3LADA KVEVTAADGSS---------QVLDTENVILASGSKP-V-EI---PPAP-V-D----QD--
      EEEEECCCCEE~~~~~~~~~EEEEEEEEEEECCEEE~E~CC~~~CCCC~C~C~~~~CC~~
1LPFA QVEVTGLDGKT---------QVLEAENVIIASGSRP-V-EI---PPAP-L-S----DD--
      EEEEECCCCEE~~~~~~~~~EEEEEEEEEEECCEEE~E~CC~~~CCCC~C~C~~~~CC~~
1EBDA TVRVV---------NGD-SAQTYTFKNAIIATGSRP-IELP---NFKF-S-N----RI--
      EEEEE~~~~~~~~~ECC~CEEEEEEEEEEEECCEEE~ECCC~~~CCCC~C~C~~~~EE~~
1JEHA KIRVTPV---DGLEGTVKEDHILDVKNIIVATGSEV-T------PFPG-I-EIDEEKI--
      EEEEEEC~~~CCCCCCCCCCEEEEEEEEEEEECEEE~E~~~~~~CCCC~C~CCCCCEE~~
1DXLA EISVDTIEGENT---------VVKGKHIIIATGSDV-K-SL---PGVT-I-DEK--KI--
      EEEEECCCCCEE~~~~~~~~~EEEEEEEEEECCEEE~E~CC~~~CCCC~C~CCC~~EE~~
1ZMCA QVTA------TKADGG---TQVIDTKNILIATGSEV-TPFP---GITI-D-E----DT--
      EEEE~~~~~~ECCCCE~~~EEEEEEEEEEEECCEEE~ECCC~~~CCCC~C~C~~~~CE~~
2A8XA TLLV------DLNDGG---TESVTFDNAIIATGSST-R-LV---PGTS-L-SA---NV--
      EEEE~~~~~~EECCCE~~~EEEEEEEEEEEECCEEE~E~CC~~~CCCC~C~CC~~~CE~~
1ZK7A SLTVRLNEG---------GERVVMFDRCLVATGASP-A-VP---PIPG-L-K----ESPY
      EEEEEECCC~~~~~~~~~CEEEEEEEEEEEECCEEE~E~CC~~~CCCC~C~C~~~~CCCE
1XDIA PGLARHRIKATAAD-GSTSEH--EADVVLVATGASPRI-LP---SAQP-DGE----RI--
      CCCCEEEEEEECCC~CEEEEE~~EEEEEEEECCEEEEC~CC~~~CCCC~CCC~~~~EE~~


 164  -I-SSD-----EFFNIKE-S---K-KIGI-VGSGYIAVE---LINVIKRLGID-SYIFAR 207
1ONFA -I-SSD-----EFFNIKE-S---K-KIGI-VGSGYIAVE---LINVIKRLGID-SYIFAR
      ~E~ECH~~~~~HHHCCCC~C~~~E~EEEE~ECCCHHHHH~~~HHHHHHHCCEE~EEEEEE
1GERA -I-DSD-----GFFALPALP---E-RVAV-VGAGYIAVE---LAGVINGLGAK-THLFVR
      ~E~ECH~~~~~HHCCCCCCC~~~E~EEEE~ECCCHHHHH~~~HHHHHHHHCEE~EEEEEE
1BWCA -I-TSD-----GFFQLEE-L---PGRSVI-VGAGYIAVE---MAGILSALGSK-TSLMIR
      ~E~EHH~~~~~HHCCCCC~C~~~CEEEEE~ECCHHHHHH~~~HHHHHHHHCEE~EEEEEE
1ZDLA -I-TSD-----DIFWLKE-S---PGKTLV-VGASYVALE---CAGFLTGIGLD-TTVMMR
      ~E~ECC~~~~~HHHCCCC~C~~~CCEEEE~EECCCHHHH~~~HHHHHHHHCEE~EEEEEC
1AOGA -I-SSN-----EAFYLPEPP---R-RVLT-VGGGFISVEFAGIFNAYKPKDGQ-VTLCYR
      ~E~EHH~~~~~HHHCCCCCC~~~E~EEEE~ECCHHHHHHHHHHHHHCCCCCEE~EEEEEE
1H6VA -I-SSD-----DLFSLPY-C---PGKTLV-VGASYVALE---CAGFLAGIGLD-VTVMVR
      ~E~ECH~~~~~HHHCCCC~C~~~CCEEEE~ECCHHHHHH~~~HHHHHHHHCEE~EEEEEC
1FEAA -I-TSN-----EAFYLDE-A---P-KRALCVGGGYISIEFAGIFNAYKARGGQ-VDLAYR
      ~E~EHH~~~~~HHHCCCC~C~~~C~EEEEEECCHHHHHHHHHHHHHHCCCCEE~EEEEEE
3LADA -V-IVDSTGALDFQNV---P---G-KLGV-IGAGVIGLE---LGSVWARLGAE-VTVLEA
      ~E~EEECHHHHCCCCC~~~C~~~E~EEEE~ECCHHHHHH~~~HHHHHHHHCEE~EEEEEE
1LPFA -I-IVD-----STGALEF-QAVPK-KLGV-IGAGVIGLE---LGSVWARLGAE-VTVLEA
      ~C~EEE~~~~~HHHHHCC~CCCCE~EEEE~ECCCHHHHH~~~HHHHHHHHCEE~EEEEEE
1EBDA -L-DST-----GALNLGEVP---K-SLVV-IGGGYIGIE---LGTAYANFGTK-VTILEG
      ~E~EHH~~~~~HHHHCCCCC~~~E~EEEE~ECCHHHHHH~~~HHHHHHHHCEE~EEEEEE
1JEHA -V-SST-----GALSLKEIP---K-RLTI-IGGGIIGLE---MGSVYSRLGSK-VTVVEF
      ~E~CHH~~~~~HHHCCCCCC~~~E~EEEE~ECCCHHHHH~~~HHHHHHHHCEE~EEEEEC
1DXLA -V-SST-----GALALSEIP---K-KLVV-IGAGYIGLE---MGSVWGRIGSE-VTVVEF
      ~E~CHH~~~~~HHHCCCCCC~~~E~EEEE~EECCHHHHH~~~HHHHHHHHCEE~EEEEEC
1ZMCA -IVSST-----GALSLKKVP---E-KMVV-IGAGVIGVE---LGSVWQRLGADVTAVEFL
      ~EEEHH~~~~~HHHCCCCCC~~~E~EEEE~ECCCHHHHH~~~HHHHHHHHCEEEEEEEEE
2A8XA -V-TYE-----EQILSRELP---K-SIII-AGAGAIG-E---FGYVLKNYGVD-VTIVEF
      ~E~EHH~~~~~HHCCCCCCC~~~E~EEEE~ECCCCCC~C~~~HHHHHHHHCEE~EEEEEE
1ZK7A WT-STE-----ALASDTI-P---E-RLAV-IGSSVVALE---LAQAFARLGSK-VTVLAR
      EE~HHH~~~~~HHHCCCC~C~~~E~EEEE~ECCCHHHHH~~~HHHHHHHHCEE~EEEEEC
1XDIA -L-TWR-----QLYDLDALP---D-HLIV-VGSGVTGAE---FVDAYTELGVP-VTVVAS
      ~E~ECC~~~~~CCCCCCCCC~~~C~EEEE~ECCCCCHHH~~~HHHHHHCCCEE~EEEEEE


 208  GNRILRKF-DESVINVLENDMKKNNINIV-----TFADVVEI-----KK-VSD-K--NL- 251
1ONFA GNRILRKF-DESVINVLENDMKKNNINIV-----TFADVVEI-----KK-VSD-K--NL-
      EECCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~CCC~C~~EE~
1GERA KHAPLRSF-DPMISETLVEVMNAEGPQLH-----TNAIPKAV-----VK-NTD-G--SL-
      ECCCCCCC~CHHHHHHHHHHHHHCCEEEE~~~~~ECEEEEEE~~~~~EE~CCC~C~~EE~
1BWCA HDKVLRSF-DSMISTNCTEELENAGVEVL-----KFSQVKEV-----KKTLSG-L--EV-
      EECCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EECCCC~E~~EE~
1ZDLA -SIPLRGF-DQQMSSLVTEHMESHGTQFL-----KGCVPSHI-----KK-LPT-N--QL-
      ~CCCCCCC~HHHHHHHHHHHHHHCCEEEE~~~~~ECEEEEEE~~~~~EE~CCC~C~~EE~
1AOGA GEMILRGF-DHTLREELTKQLTANGIQIL-----TKENPAKV-----EL-NAD-G--SK-
      EECCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECCCEEEE~~~~~EE~CCC~C~~EE~
1H6VA -SILLRGF-DQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLK-VTA-K--ST-
      ~CCCCCCC~CHHHHHHHHHHHHHHCEEEEECEEEEEEEEEECCCCCEEE~EEE~E~~CC~
1FEAA GDMILRGF-DSELRKQLTEQLRANGINVR-----THENPAKV-----TK-NAD-G--TR-
      ECCCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECCCEEEE~~~~~EE~CCC~C~~EE~
3LADA MDKFLPAV-DEQVAKEAQKILTKQGLKIL-----LGARVTG------TE-VKN-K--QV-
      EECCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEE~~~~~~EE~ECC~C~~EE~
1LPFA LDKFLPAA-DEQIAKEALKVLTKQGLNIR-----LGARVT-A-----SE-VKK-K--QV-
      EECCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEE~E~~~~~EE~ECC~C~~EE~
1EBDA AGEILSGF-EKQMAAIIKKRLKKKGVEVV-----TNALAKGA-----EE-RED-G--VT-
      ECCCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~CCC~C~~EE~
1JEHA QPQIGASM-DGEVAKATQKFLKKQGLDFK-----LSTKVISA-----KR-NDD-K--NVV
      CCCCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~ECC~C~~CEE
1DXLA ASEIVPTM-DAEIRKQFQRSLEKQGMKFK-----LKTKVVGV-----DT-SGDGV--KL-
      CCCCCCCC~CHHHHHHHHHHHHCCCEEEE~~~~~ECEEEEEE~~~~~EE~CCCEE~~EE~
1ZMCA GHVGGVGI-DMEISKNFQRILQKQGFKFK-----LNTKVTGA-----TK-KSD-GKIDV-
      ECCCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~CCC~CEEEE~
2A8XA LPRALPNE-DADVSKEIEKQFKKLGVTIL-----TATKVESI-----AD-GGS-Q--VT-
      ECCCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~CCC~E~~EE~
1ZK7A NTLFFRE--DPAIGEAVTAAFRAEGIEVL-----EHTQASQV-----AH-M-D-G--EF-
      CCCCCCC~~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~C~C~C~~EE~
1XDIA QDHVLPYE-DADAALVLEESFAERGVRLF-----KNARAASV-----TR-TG--A--GV-
      EECCCCCC~CHHHHHHHHHHHHHHCEEEE~~~~~ECEEEEEE~~~~~EE~CC~~C~~EE~


 252  SI----HLS-D--G--RI-----YE-H----F--DHVIYCVGRSPDTENLKLEKLNVE-T 289
1ONFA SI----HLS-D--G--RI-----YE-H----F--DHVIYCVGRSPDTENLKLEKLNVE-T
      EE~~~~EEC~C~~C~~EE~~~~~EE~C~~~~E~~EEEEEECCEEEECCCCCCCCCCEE~E
1GERA TL----ELE-D--G--R------SE-T----V--DCLIWAIGREPANDNINLEAAGVK-T
      EE~~~~EEC~C~~C~~E~~~~~~EE~E~~~~E~~EEEEEECCEEEECCCCCHHHHCEE~E
1BWCA SM----VTAVP--G--RLPVMTMIP-D----V--DCLLWAIGRVPNTKDLSLNKLGIQ-T
      EE~~~~EEECC~~C~~CCEEEEEEE~C~~~~E~~EEEEEECCEEEECCCCCHHHHCEE~E
1ZDLA QVTWEDHAS-G--K--ED-----TG-T----F--DTVLWAIGRVPETRTLNLEKAGIS-T
      EEEEEEECC~C~~E~~EE~~~~~EE~E~~~~E~~EEEEEECCEEECCCCCCCCCCCEE~E
1AOGA SV----TFE-S--G--KK-----MD------F--DLVMMAIGRSPRTKDLQLQNAGVM-I
      EE~~~~EEC~C~~C~~EE~~~~~EE~~~~~~E~~EEEEEECCEEEECHHHCHHHCCEE~E
1H6VA N-------S-E--E--TI-----ED-E----F--NTVLLAVGRDSCTRTIGLETVGVK-I
      C~~~~~~~C~C~~E~~EE~~~~~EC~E~~~~E~~EEEEECCCEEEECCCCCCCCCCCC~C
1FEAA HV----VFE-S--G--AE-----AD------Y--DVVMLAIGRVPRSQTLQLEKAGVEVA
      EE~~~~EEC~C~~C~~EE~~~~~EE~~~~~~E~~EEEEEECEEEEECCCCCHHHHCEEEC
3LADA TV----KFV-DAEG--EK-----SQ-A----F--DKLIVAVGRRPVTTDLLAADSGVT-L
      EE~~~~EEE~ECCE~~EE~~~~~EE~C~~~~E~~EEEEEECEEEEECCCCCCCCCCEE~E
1LPFA TV----TFT-DANG--EQ-----KE-T----F--DKLIVAVGRRPVTTDLLAADSGVT-L
      EE~~~~EEE~CCCC~~EE~~~~~EE~E~~~~E~~EEEEEEEEEEEECCCCCCCCCCEE~E
1EBDA VT----YEA-N--G--ET-----KTID----A--DYVLVTVGRRPNTDELGLEQIGIKMT
      EE~~~~EEE~C~~C~~EE~~~~~EEEE~~~~E~~EEEEEECCEEECCCCCCHHHHCCCCC
1JEHA EI----VVE-D--T--KT-----NK-QENLEA--EVLLVAVGRRPYIAGLGAEKIGLE-V
      EE~~~~EEE~E~~E~~CC~~~~~CE~EEEEEE~~EEEEEECCEEEECCCCCCHHHCEE~E
1DXLA TV----EPS-A--GGEQT-----II-E----A--DVVLVSAGRTPFTSGLNLDKIGVE-T
      EE~~~~EEE~C~~CCCCE~~~~~EE~E~~~~E~~EEEEECCEEEEECCCCCCCCCCEE~E
1ZMCA SI----EAA-S--G--GK-----AE-V----ITCDVLLVCIGRRPFTKNLGLEELGIE-L
      EE~~~~EEE~C~~C~~CC~~~~~CE~E~~~~EEEEEEEEECCEEEECCCCCHHHHCCC~C
2A8XA VT----VTK-D--G--VA-----QELK----A--EKVLQAIGFAPNVEGYGLDKAGVA-L
      EE~~~~EEE~C~~C~~CE~~~~~EEEE~~~~E~~EEEEEECEEEEECCCCCHHHHCCC~C
1ZK7A VL----TTT-H--G--EL--------R----A--DKLLVATGRTPNTRSLALDAAGVT-V
      EE~~~~EEC~C~~C~~EE~~~~~~~~E~~~~E~~EEEEEEEEEEEECCCCCHHHHCEE~E
1XDIA LV----TMT-D--G--RT-----VE-G-------SHALMTIGSVPNTSGLGLERVGIQ-L
      EE~~~~EEC~C~~C~~CE~~~~~EE~E~~~~~~~EEEEEECEEEEECCCCCHHHCCCC~E


 290  N--N-N-YIVVDENQRTSVNNIYAVGDCC---MVKKSKEIEDLNLLKLYNEERYLNKKEN 342
1ONFA N--N-N-YIVVDENQRTSVNNIYAVGDCC---MVK-------------------------
      C~~C~C~EEEEECCCCCCCCCEEEECCEE~~~EEE~~~~~~~~~~~~~~~~~~~~~~~~~
1GERA NE-K-G-YIVVDKYQNTNIEGIYAVGDNT---GA--------------------------
      CC~C~C~EEECCCCCCCCCCCEEEECCCC~~~CC~~~~~~~~~~~~~~~~~~~~~~~~~~
1BWCA D--D-KGHIIVDEFQNTNVKGIYAVGDVC---G---------------------------
      C~~C~CCEEECCCCCCCCCCCEEEECCCC~~~C~~~~~~~~~~~~~~~~~~~~~~~~~~~
1ZDLA NPKN-Q-KIIVDAQEATSVPHIYAIGD---------------------------------
      CCCC~C~EEECCCCCCCCCCCEEEECC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1AOGA K--N-G-GVQVDEYSRTNVSNIYAIG----------------------------------
      C~~C~C~EEECCCCCCCCCCCEEEEC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1H6VA NEKT-G-KIPVTDEEQTNVPYIYAIGDIL---EGK-------------------------
      CCCC~C~EEECCCCCCCCCCCEEEECCEE~~~ECC~~~~~~~~~~~~~~~~~~~~~~~~~
1FEAA K--N-G-AIKVDAYSKTNVDNIYAIGD---------------------------------
      C~~C~C~EEECCCCCCCCCCEEEEECC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
3LADA DE-R-G-FIYVDDYCATSVPGVYAIG----------------------------------
      CC~C~C~EEECCCCCCCCCCCEEEEC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1LPFA DE-R-G-FIYVDDHCKTSVPGVFAIG----------------------------------
      CC~C~C~EEECCCCCCCCCCCEEEEC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1EBDA N--R-G-LIEVDQQCRTSVPNIFAIG----------------------------------
      C~~C~C~EEECCCCCCCCCCCEEEEC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1JEHA D--K-RGRLVIDDQFNSKFPHIKVVGD---------------------------------
      C~~C~CCEEECCCCCCCCCCCEEEECC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1DXLA D--KLG-RILVNERFSTNVSGVYAIG----------------------------------
      C~~CCC~EEECCCCCCCCCCCEEEEC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1ZMCA DP-R-G-RIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVE-------------
      CC~C~C~EEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH~~~~~~~~~~~~~
2A8XA T--D-R-KAIGVDDYRTNVGHIYAIG---------------DVNGL--------------
      C~~C~C~CEEECCCCCCCCCCEEEEC~~~~~~~~~~~~~~~CCCCC~~~~~~~~~~~~~~
1ZK7A NA-Q-G-AIVIDQGMRTSNPNIYAAGDCT-------------------------------
      CC~C~C~EEECCCCCCCCCCCEEEECCCC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
1XDIA G--RGN-YLTVDRVSRTLATGIYAAGDCT---GL--------------------------
      E~~ECC~EEECCCCCCCCCCCEEEECCCC~~~CC~~~~~~~~~~~~~~~~~~~~~~~~~~


 343  VTEDIFYNVQLTPVAINAGRLLADRLF-LKK-TRKTNYKLIPTVIFSHPPIGTIGLSEEA 400
1ONFA -----FYNVQLTPVAINAGRLLADRLF-LKK-TRKTNYKLIPTVIFSHPPIGTIGLSEEA
      ~~~~~CCCCCCHHHHHHHHHHHHHHHC~CCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1GERA --------VELTPVAVAAGRRLSERLF-NNKPDEHLDYSNIPTVVFSHPPIGTVGLTEPQ
      ~~~~~~~~CCCHHHHHHHHHHHHHHHC~CCCCCCCCCCCCCEEEECCCEEEEEECCCHHH
1BWCA -------KALLTPVAIAAGRKLAHRLFEYKE-DSKLDYNNIPTVVFSHPPIGTVGLTEDE
      ~~~~~~~CCCCHHHHHHHHHHHHHHHHHCCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1ZDLA VAEG---RPELTPTAIKAGKLLAQRLF-GKS-STLMDYSNVPTTVFTPLEYGCVGLSEEE
      EEEC~~~CCCCHHHHHHHHHHHHHHHC~CCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1AOGA ---DVTNRVMLTPVAINEAAALVDTVF-GTT-PRKTDHTRVASAVFSIPPIGTCGLIEEV
      ~~~CCCCCCCCHHHHHHHHHHHHHHHH~CCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1H6VA --------LELTPVAIQAGRLLAQRLY-GGS-TVKCDYDNVPTTVFTPLEYGCCGLSEEK
      ~~~~~~~~CCCHHHHHHHHHHHHHHHH~CCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1FEAA VTD----RVMLTPVAINEGAAFVDTVF-ANK-PRATDHTKVACAVFSIPPMGVCGYVEED
      CCC~~~~CCCCHHHHHHHHHHHHHHHC~CCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
3LADA ---DVVRGAMLAHKASEEGVVVAERIA-GHK-A-QMNYDLIPAVIYTHPEIAGVGKTEQA
      ~~~CCCCCCCCHHHHHHHHHHHHHHHH~CCC~C~CCCCCCCEEEECCCEEEEEECCCHHH
1LPFA ---DVVRGAMLAHKASEEGVMVAERIA-GHK-A-QMNYDLIPSVIYTHPEIAWVGKTE--
      ~~~CCCCCCCCHHHHHHHHHHHHHHHH~CCC~C~CCCCCCCEEEECCCEEEEEECCCH~~
1EBDA ---DIVPGPALAHKASYEGKVAAEAI--AGH-PSAVDYVAIPAVVFSDPECASVGYFEQQ
      ~~~CCCCCCCHHHHHHHHHHHHHHHH~~HCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1JEHA ----VTFGPMLAHKAEEEG-IAAVEML-KTG-HGHVNYNNIPSVMYSHPEVAWVGKTEEQ
      ~~~~CCCCCCCHHHHHHHH~HHHHHHH~HCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1DXLA ---DVIPGPMLAHKAEEDGVACVEYL--AGK-VGHVDYDKVPGVVYTNPEVASVGKTEEQ
      ~~~CCCCCCCCHHHHHHHHHHHHHHH~~HCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1ZMCA --------------GMAGGAVHID-------------YNCVPSVIYTHPEVAWVGKSEEQ
      ~~~~~~~~~~~~~~HHHCCCCCCC~~~~~~~~~~~~~CCCCEEEECCCEEEEEECCCHHH
2A8XA --------LQLAHVAEAQGVVAAETIA-GAE-TLTLGDHRLPRATFCQPNVASFGLTEQQ
      ~~~~~~~~CCCHHHHHHHHHHHHHHHH~CCC~CCCCCCCCCEEEECCCEEEEEECCCHHH
1ZK7A ------DQPQFVYVAAAAGTRAAINM--TGG-DAALDLTAMPAVVFTDPQVATVGYSEAE
      ~~~~~~CCCCCHHHHHHHHHHHHHHH~~HCC~CCEEECCCCEEEECCCEEEEEECCCHHH
1XDIA --------LPLASVAAMQGRIAMYHAL-GEG-VSPIRLRTVAATVFTRPEIAAVGV-PQS
      ~~~~~~~~CCCHHHHHHHHHHHHHHHH~CCC~CCEEECCCCEEEECCCEEEEEECC~CHH


 401  AIQIYGKENVKIYESKFTNLFFSVYDIEPELKEKT-YL-KLVCVGK-D-ELIKGLHIIGL 456
1ONFA AIQIYGKENVKIYESKFTNLFFSVYDIEPELKEKT-YL-KLVCVGK-D-ELIKGLHIIGL
      HHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCEE~EE~EEEEECC~C~CCCEEEEEEEC
1GERA AREQYGDDQVKVYKSSFTAMYTAV----TTHRQPC-RM-KLVCVGS-E-EKIVGIHGIGF
      HHHHCCCCCEEEEEEEEEEHHHHC~~~~CCCEEEE~EE~EEEEECC~C~CEEEEEEEECC
1BWCA AIHKYGIENVKTYSTSFTPMYHAV----TKRKTKC-VM-KMVCANK-E-EKVVGIHMQGL
      HHHHHCCCEEEEEEEEEECCCCCC~~~~CCCCCEE~EE~EEEEECC~C~CEEEEEEEEEC
1ZDLA AVALHGQEHVEVYHAYYKPLEFTVADRD---ASQC-YI-KMVCMREPP-QLVLGLHFLGP
      HHHHHCCCEEEEEEEEECCHHHHCCCCC~~~CCCE~EE~EEEEEECCC~CEEEEEEEEEC
1AOGA ASKRY--EVVAVYLSSFTPLMHKV----SGSKYKT-FVAKIITNHS-D-GTVLGVHLLGD
      HCCCC~~EEEEEEEEEEECHHHHH~~~~HCCCCCE~EEEEEEEEEC~C~CEEEEEEEECC
1H6VA AVEKFGEENIEVYHSFFWPLEWTVPSRD---NNKC-YA-KVICNLK-DNERVVGFHVLGP
      HHHHHCCCCEEEEEEEECCHHHHCCCCC~~~CCEE~EE~EEEEECC~CCCEEEEEEEEEC
1FEAA AAKKY--DQVAVYESSFTPL---MHNISGSTYKKF-MV-RIVTNHA-D-GEVLGVHMLGD
      HHHCC~~EEEEEEEEEEECC~~~HHHHHCCCCCEE~EE~EEEEEEC~C~CEEEEEEEECC
3LADA LKAEGVAINVGVFPFAASGRAMAAND------TAG-FV-KVIADAK-T-DRVLGVHVIGP
      HHHHCEEEEEEEECCCCHHHHHHHCC~~~~~~CCC~EE~EEEEEEC~C~CEEEEEEEECC
1LPFA --QTLKAEGVEVNVGTFP---FAASGRAMAANDTT-GLVKVIADAK-T-DRVLGVHVIGP
      ~~HHHHHHCEEEEEEEEC~~~CCCHHHHHHHCCCC~CEEEEEEEEC~C~EEEEEEEEECC
1EBDA A----KDEGIDVIAAKFP---FAANGRALALNDTDGFL-KLVVRKE-D-GVIIGAQIIGP
      H~~~~HHHCEEEEEEEEC~~~CCCCHHHHHHCCCCCEE~EEEEEEC~C~CCCEEEEEECC
1JEHA LKEA----GIDYKIGKFP--FAANSRAKTNQDTEG-FV-KILIDSK-T-ERILGAHIIGP
      HHHH~~~~CEEEEEEEEC~~CCCHHHHHHHCCCCC~EE~EEEEEEC~C~CEEEEEEEEEE
1DXLA V----KETGVEYRVGKFP--FMANSRAKAIDNAEG-LV-KIIAEKE-T-DKILGVHIMAP
      H~~~~HHHCEEEEEEEEC~~CCCHHHHHHHCCCCC~EE~EEEEEEC~C~CEEEEEEEEEE
1ZMCA ----LKEEGIEYKVGKFP--FAANSRAKTNADTDG-MV-KILGQKS-T-DRVLGAHILGP
      ~~~~HHHHCEEEEEEEEC~~CCCCHHHHHHCCCCC~EE~EEEEEEC~C~CEEEEEEEECC
2A8XA A----RNEGYDVVVAKFP--FTANAKAHGVGDPSG-FV-KLVADAK-H-GELLGGHLVGH
      H~~~~HHHCEEEEEEEEC~~CCCCHHHHHHCCCCC~EE~EEEEEEC~C~CCEEEEEEEEE
1ZK7A A------HHDGIETDSRTLTLDNVPRALANFDTRG-FI-KLVIEEG-S-HRLIGVQAVAP
      H~~~~~~HHHCEEEEEEEECCCCHHHHHHHCCCCC~EE~EEEEEEC~C~CEEEEEEEEEC
1XDIA VIDAGSVAARTIMLPLRTNARAKMSEM-----RHG-FV-KIFCRRS-T-GVVIGGVVVAP
      HHHHCCEEEEEEEEECCCCHHHHHHCC~~~~~CEE~EE~EEEEEEC~C~CEEEEEEEEEC


 457  NADEIVQGFAVALKMNATKKDF-DETIPIHPTAAEEFLTLQPWMK 500
1ONFA NADEIVQGFAVALKMNATKKDF-DETIPIHPTAAEEFLTLQ~~~~
      CHHHHHCHHHHHHHHCCCHHHH~HHCCCCCCCCHHHCCCCC~~~~
1GERA GMDEMLQGFAVALKMGATKKDF-DNTVAIHPTAAEEFVTMR~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCHHHCCCC~~~~
1BWCA GCDEMLQGFAVAVKMGATKADF-DNTVAIHPTSSEELVTLR~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCCCCCCCC~~~~
1ZDLA NAGEVTQGFALGIKCGASYAQV-MQTVGIHPTCSEEVVKL~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCHHHHHC~~~~~
1AOGA NAPEIIQGIGICLKLNAKISDF-YNTIGVHPTSAEELCSMR~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCCHHHCCC~~~~
1H6VA NAGEVTQGFAAALKCGLTKQQL-DSTIGIHPVCAEIFTTL~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCHHHHHHCC~~~~~
1FEAA SSPEIIQSVAICLKMGAKISDF-YNTIGVHPTSAEELCSMR~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCCCCCCCC~~~~
3LADA SAAELVQQGAIAMEFGTSAEDL-GMMVFAHPALSE~~~~~~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCH~~~~~~~~~~
1LPFA SAAELVQQGAIGMEFGTSAEDL-GMMVFSHPTLSE~~~~~~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCH~~~~~~~~~~
1EBDA NASDMIAELGLAIEAGMTAEDI-ALTIHAHPTLGE~~~~~~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCCCH~~~~~~~~~~
1JEHA NAGEMIAEAGLALEYGASAEDV-ARVCHAHPTLSEAF~~~~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCHHHHH~~~~~~~~
1DXLA NAGELIHEAAIALQYDASSEDI-ARVCHAHPTMSE~~~~~~~~~~
      CHHHHHHHHHHHHHCCCCHHHH~HHCCCCCCCCHH~~~~~~~~~~
1ZMCA GAGEMVNEAALALEYGASCEDI-ARVCHAHPTLSEAF~~~~~~~~
      CHHHHHHHHHHHHHHCCCHHHH~HHCCCCCCCHHHHH~~~~~~~~
2A8XA DVAELLPELTLAQRWDLTASEL-ARNVHTHPTS~~~~~~~~~~~~
      CCCCCHHHHHHHHHCCCHHHHH~HHCCCCCCCC~~~~~~~~~~~~
1ZK7A EAGELIQTAALAIRNRMTVQELADQLFP~~~~~~~~~~~~~~~~~
      CHHHHHHHHHHHHHHCCCHHHHHHCCCC~~~~~~~~~~~~~~~~~
1XDIA IASELILPIAVAVQNRITVNEL-AQTLAVYPS~~~~~~~~~~~~~
      CHHHHHHHHHHHHHCCCCHHHH~HHCCCCCCC~~~~~~~~~~~~~




PSI-BLAST ALIGNMENTS - 49 SEQUENCES USED BY JNET, TRANSSEC, and PSIPRED
Blast e-value: 2.77315E-111
1   >gi|33861124|ref|NP_892685.1| probable glutathione reductase (NADPH) [Prochlorococcus marinus subsp. pastoris str. CCMP1378] >gnl|BL_ORD_ID|766800 probable glutathione reductase (NADPH) [Prochlorococcus marinus subsp. pastoris str. CCMP1986]
match: ----FDLI-VLGAGSGGLAAAKRAASY------GAKVAIIEV--NK---------IGGTCVI-RGCVPKKLMVYA-ANNRRN-M---LSSE--GYGL-ISK---EITFESNILLKN-VREEVSRLSVL-HSNS--LKK--LNVKVFEG-LGR-F-LNQN-------TVEVVCPK-TKNIL------RKVS--------AKS-I-LISVGGKP---K---KLNIPG---T--DFA----W--TSD--DIFE-L-K-D-F-PK-K-L-----LIVGGGYIACEFA-SI-FKN---LGTEVTQLIRGE-NL--L-NGFDKD-L--S-ECLE-KSMTSLGINL--KF--KNQLKSI-KKI-ND-G----LE---S-TLESG-SKL-------LTDNILVATGREPSLKRLN--LDTLNLKM----DGIYLE-VNELN--KT--S---ISNIFAI--GD---I---------------------------V-K----RPNLTPVAIEQG-RVF---A-DNYFAALK---R--KVNY--ENI-PKAVFTIPEISTVGLSEEKANEI-YSEVNVQVFKC-NFTPMSNTF----KKNKS-KCML--KLV-VNKKNDKVL-GCHMFGEAA--SEII-QMVAVSLNTGI--TKKDFDTTMALHPTISEEFVT-M--------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 5.01624E-110
2   >gi|136619|sp|P13110|TYTR_TRYCO Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine reductase) >gnl|BL_ORD_ID|880574 trypanothione-disulfide reductase (EC 1.8.1.12) - Trypanosoma congolense >gnl|BL_ORD_ID|880574 trypanothione reductase
match: ----FDLV-IIGAGSGGLEAGWNAATLYK-----KRVAVVDVQTVHGPPF-FA-ALGGTCVN-VGCVPKKLMVTG-AQYMDQ-LRE-SA----GFGWEFDA--STIKANWKTLIAA-KNAAVLDINKS-YEDM--FKDT-EGLEFFLG-WGA-L-EQKN--------V-VTVRE-GAD------PKSKVKER----LQAEH-I-IIATGSWP---QM---LKIPG--I---EHC----I--SSN--EAFY-L-E-E-P-PR-R-V-----LTVGGGFISVEFA-GI-FNAYKPVGGKVTLCYRNN-PI--L-RGFDYT-L--R-QELT-KQLVANGIDI----MTNENPSKI-ELN-PD-G-SKHVT-F-----ESG-KTLD-------VDVVMMAIGRLPRTGYLQ--LQTVGVNLTDK--G-AIQ-VDEFS--RT--N---VPNIYAI--GD-------------------------------VTG----RIMLTPVAINEG-ASV---V-DTIFGSKP---R--KTDH--TRV-ASAVFSIPPIGTCGLTEEEAAKS-F--EKVAVYLS-CFTPLMHNISG--SKYK--KFVA--KII-TDHGDGTVV-GVHLLGDSS--PEII-QAVGICMKLNA--KISDFYNTIGVHPTSAEELCS-MRTP-----------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.47587E-109
3   >gi|1942669|pdb|1FEA|A Chain A, Unliganded Crithidia Fasciculata Trypanothione Reductase At 2.2 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain B, Unliganded Crithidia Fasciculata Trypanothione Reductase At 2.2 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain C, Unliganded Crithidia Fasciculata Trypanothione Reductase At 2.2 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain D, Unliganded Crithidia Fasciculata Trypanothione Reductase At 2.2 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain A, Unliganded Crithidia Fasciculata Trypanothione Reductase At 2.0 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain B, Unliganded Crithidia Fasciculata Trypanothione Reductase At 2.0 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain A, Unliganded Crithidia Fasciculata Trypanothione Reductase At 1.7 Angstrom Resolution >gnl|BL_ORD_ID|275408 Chain B, Unliganded Crithidia Fasciculata Trypanothione Reductase At 1.7 Angstrom Resolution
match: ----YDLV-VIGAGSGGLEAGWNAASLHK-----KRVAVIDLQKHHGPPH-YA-ALGGTCVN-VGCVPKKLMVTG-ANYMDT-IRE-SA----GFGWELDR--ESVRPNWKALIAA-KNKAVSGINDS-YEGM--FADT-EGLTFHQG-FGA-L-QDNH-------TVLVRESA-DPN-----------SA-VLETLDTEY-I-LLATGSWP---Q---HLGIEG--D---DLC----I--TSN--EAFY-L-D-E-A-PK-R-A-----LCVGGGYISIEFA-GI-FNAYKARGGQVDLAYRGD-MI--L-RGFDSE-L--R-KQLT-EQLRANGINVR----THENPAKV-TKN-AD-G-TRHV--V-F---ESG-AEAD-------YDVVMLAIGRVPRSQTLQ--LEKAGVEVA-K-NG-AIK-VDAYS--KT--N---VDNIYAI--GD-------------------------------VTD----RVMLTPVAINEG-AAF---V-DTVFANKP---R--ATDH--TKV-ACAVFSIPPMGVCGYVEEDAAKK-Y--DQVAVYES-SFTPLMHNISG--STYK--KFMV--RIVTNHADGE-VL-GVHMLGDSS--PEII-QSVAICLKMGA--KISDFYNTIGVHPTSAEELCS-MRTP-----------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 4.68732E-108
4   >gi|33601404|ref|NP_888964.1| putative glutathione reductase [Bordetella bronchiseptica RB50] >gnl|BL_ORD_ID|6970 putative glutathione reductase [Bordetella bronchiseptica]
match: ----FDLY-VIGAGSGGVRAARFAAGY------GARVAVAE---SRY--------LGGTCVN-VGCVPKKLLVYG-AHFHED-FEQ-AA----GFGWNPG----RPEFDWPTLIAN-KNREIERLNGI-YRNL--LVN--SGVALHEG-HAR-I-VDPH-------TVEI---N-GQRH----------S--------AQH-I-LVATGGWP---FVP---DIPG---K--EHA----I--TSN--DAFF-L-P-E-L-PR-R-V-----LVVGGGYIAVEFA-SI-FNG---LGAQTVQVYRRE-LF--L-RGFDGS-V--R-EHLR-DELVKKGLDL--RF--NTDVERI-DKR-AD-G-V--LA-V---TLSDG-SVLET-------DCVFYATGRRAMLDDLG--LENTGVRLA-E-SG-YIE-VDDEY--RT--S---EPSILAI--GD---V---------------------------I-G----RVPLTPVALAEG-MAV---A-RRLFRPQEY--R--KVDY--DLI-PTAVFSLPNIGTVGLTTEQALER--GF-RVTRYES-RFRPMKLTL----TQSQE-KTLM--KLV-VDADSQKVL-GCHMVGPDA--GEIV-QGLAVALKAGA--TKQVFDDTIGIHPTAAEEFVT-MRTAT----------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.2359E-107
5   >gi|100037|pir||S22384 dihydrolipoamide dehydrogenase (EC 1.8.1.4) precursor - garden pea
match: -----DVV-IIGGGPGGYVAAIKAAQL------GFKTTCIE----------KRGALGGTCLN-VGCIPSKALLHS-SHMYHE-AKHSFA-N-HGV--KVS----NVEIDLAAMMGQ-KDKAVSNLT----RGIEGLFKK-NKVTYVKG-YGK-F-VSPS-------EISVDTIE-GENTV----------------VKGKH-I-IIATGSDVK--SLPG-VTID-------EKK----I-VSST--GALA-L-S-E-I-PK-K-L-----VVIGAGYIGLEMG-SV-WGR---IGSEVTVVEFAS-EI--V-PTMDAE-I--R-KQFQ-RSLEKQGMKF--KL--KTKVVGV-DTS-GD-G----VK-L---TVEPS-AGGEQTIIE--ADVVLVSAGRTPFTSGLN--LDKIGVE-TDK-LGR-IL-VNERF--ST--N---VSGVYAI--GD---V---------------------------IPG-----PMLAHKAEEDG-VAC---V-EYL-AGK---VG--HVDY--DKV-PGVVYTNPEVASVGKTEEQ-VKE-TG---VE-YRVGKF-PFMAN-SRAKAIDNA-EGLV--KII-AEKETDKIL-GVHIMAPNA--GELIHEA-AIALQYDA--SSEDIARVCHANPTMSEAI------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 7.42985E-102
6   >gi|26333601|dbj|BAC30518.1| unnamed protein product [Mus musculus]
match: ----FDYL-VIGGGSGGLASARRAAEL------GARAAVVE---SHK--------LGGTCVN-VGCVPKKVMWNT-AVHSEF-MHD-HV-D-YGFQSCEG------KFSWHVIKQK-RDAYVSRLNTI-YQNN--LTK--SHIEIIHG-YAT-F-ADGPRP-----TVEV---N-GKK----------FT--------APH-I-LIATGGVP---TVPHESQIPG---A--SLG----I--TSD--GFFQ-L-E-D-L-PS-R-S-----VIVGAGYIAVEIA-GI-LSA---LGSKTSLMIRHD-KV--L-RNFDSL-I--S-SNCT-EELENAG--V--EVLKFTQVKEV-KKT-SS-G-L-ELQ-V-V-TSVPG-RKPTTTMIPDV-DCLLWAIGRDPNSKGLN--LNKVGIQ-TDE-KG-HIL-VDEFQ--NT--N---VKGVYAV--GD---V---------------------------C-G----KALLTPVAIAAG-RKL---A-HRLFECKQD--S--KLDY--DNI-PTVVFSHPPIGTVGLTEDEAVHK-YGKDNVKIYST-AFTPMYHAV----TTRKT-KCVM--KMVCANKE-EKVV-GIHMQGIGC--DEML-QGFAVAVKMGA--TKADFDNTVAIHPTSSEELVT-LR-------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 8.29477E-102
7   >gi|22995260|ref|ZP_00039739.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes [Xylella fastidiosa Dixon]
match: -------V-VLGAGPGGYTAAFRAADL------GLDTVLVE----RYP------NLGGVCLN-VGCIPSKALLHA-AAVID---EAAHAST-FGIDF---G-KPKITLD--TLREY-KQNVVNKLT----AGLAVMAKQ-RKVRTVTG-IAH-F-VSPN-------TLDITAAD-GSTQ----------------RLHFQQ-C-IIATGSHPV--KLP---NFPW--DD-PRI-----M--DST--DALE-L-A-E-V-PK-K-L-----LVVGGGIIGLEMA-TV-YNA---LGSHVTIVEFMD-QI--I-PGTDKD-L--V-KPLA-DRMKKQGIEI--HL--NTKASHV--K--AD-K-KG-IT-V-SFEA-PT-QGTQPALKTSTYDRVLVAVGRTPTGNNIS--AEKAGVNVTER--G-FIP-VDRQM--RS--N---VPHIFAI--GD-------------------------------IVG----NPMLAHKATHEG-K-L---A-AEVAAAETESGK--HREWVARVI-PSVAYTNPEIAWIGMTETEAKAK--GL-NIGV--A-KF-PWVAS-GRAIGIGRT-EGFT--KLI-FDEDTHRII-GGAIVGVHA--GDLLAE-IGLAIEMGA--EAEDISHTIHAHPTLSESI------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.29054E-96
8   >gi|15807510|ref|NP_296246.1| 2-oxo acid dehydrogenase, lipoamide dehydrogenase E3 component [Deinococcus radiodurans] >gnl|BL_ORD_ID|372655 dihydrolipoamide dehydrogenase (EC 1.8.1.4) DR2526 [similarity] - Deinococcus radiodurans (strain R1) >gnl|BL_ORD_ID|372655 2-oxo acid dehydrogenase, lipoamide dehydrogenase E3 component [Deinococcus radiodurans]
match: ----FDVL-VIGGGPAGYVAAIRAAQL------GFKTACVD----AFERG-GKPSLGGTCLN-VGCIPSKALLDS-SERFEM-ISHDTA-E-HGI--QVAQ-P---QIDVSKMLAR-KDGVVDKLTG----GVAFLFRK-NKVTSFHG-YGK-L-VRQD---GQEWVVD---AA-GTE------------------VKAKN-V-IVATGSNPR--ALPG-VPFGG-------HI----V-ENS---GALQ-I-D-Q-V-PG-K-L-----GVIGAGVIGLELG-SV-WRR---LGAQVTILEAMP-GF--L-MAADDA-I--A-KEAL-KQFQKQGLDF--HF--GVKIGEI--KQ-DDSG----VT-V-TYE-ENG-SQVTAQ-----FDKLIVSIGRVPNTGGLN--ADGVGLAL-DE-RG-FVK-VDQHY--RT--N---LPGVYAI--GD-------------------------------VIG----GAMLAHKAEEEG-VAL---A-E-MIAGQA---G--HVNY--DVI-PWIIYTSPEIAWAGLTEKQAKER--G---LNV-KTGQF-PFSAN-GRALGHGDP-RGFV--KVV-ADAQTDKLL-GVHMIGGGV--SELIGEIVAI-MEFGG--SAEDLARTIHAHPTLSEVVKE----------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.51267E-95
9   >gi|15826394|pdb|1JEH|A Chain A, Crystal Structure Of Yeast E3, Lipoamide Dehydrogenase >gnl|BL_ORD_ID|355692 Chain B, Crystal Structure Of Yeast E3, Lipoamide Dehydrogenase
match: ----HDVV-IIGGGPAGYVAAIKAAQL------GFNTACVE----------KRGKLGGTCLN-VGCIPSKALLNN-SHLFHQMHTE--AQK-RGIDVNGD-----IKINVANFQKA-KDDAVKQLTG----GIELLFKK-NKVTYYKGN-GS-F-EDETK-------IRVTPVD-GLEG----------TVKEDHILDVKN-I-IVATGSEVT--PFPG-IEID------EE----K-I-VSST--GALS-L-K-E-I-PK-R-L-----TIIGGGIIGLEMG-SV-YSR---LGSKVTVVEFQP-QIG---ASMDGE-V--A-KATQ-KFLKKQGLDF--KL--STKV--ISAKR-NDDK-NV-VE-IVVEDTKTN-KQ-ENLE----AEVLLVAVGRRPYIAGLG--AEKIGLEV-DK-RGRLV--IDDQF--NS--K---FPHIKVV--GD-------------------------------VT----FGPMLAHKAEEEG-IAA---V-EMLKTGH----G--HVNY--NNI-PSVMYSHPEVAWVGKTEEQ-LKE-AG---ID-YKIGKF-PFAAN-SRAKTNQDT-EGFV--KIL-IDSKTERIL-GAHIIGPNA--GEMIAEA-GLALEYGA--SAEDVARVCHAHPTLSEAFKE----------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 4.08518E-93
10  >gi|1706442|sp|P31052|DLD2_PSEPU Dihydrolipoamide dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) (LPD-GLC) (Glycine oxidation system L-factor) >gnl|BL_ORD_ID|887120 lipoamide dehydrogenase
match: ---KFDVV-VIGAGPGGYVAAIKAAQL------GLKTACIEKYTDA---E-GKLALGGTCLN-VGCIPSKALLDS-SW---K-YKE--AKE--SFNVHGIS-TGEVKMDVAAMVGR-KAGIVKNLTGG-VAT---LFKA-NGVTSIQG-HGK-L-LAGKK-------VEVTKAD-GTTEV----------------IEAEN-V-ILASGSRPI--DIPP-APVD------QNVI----V--DST--GALE-F-Q-A-V-PK-R-L-----GVIGAGVIGLELG-SV-WAR---LGAEVTVLEALD-TF--L-MAADTA-V--S-KEAQ-KTLTKQGLDI--KLGARVTGSKV------N-G-N-EVE-V-TYTNAEG----EQKI---TFDKLIVAVGRRPVTTDLL--AADSGVTI-DE-RG-YIF-VDDYC--AT--S---VPGVYAI--GD---V---------------------------VRG-----MMLAHKASEEG-IMV---V-ERIKGHK----A--QMNY--DLI-PSVIYTHPEIAWVGKTE-QALKA-EGVE-VNV--G-TF-PFAAS-GRAMAANDT-GGFV--KVI-ADAKTDRVL-GVHVIGPSA--AELVQQG-AIAMEFGT--SAEDLGMMVFSHPTLSEAL------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.24596E-90
11  >gi|23049840|ref|ZP_00076877.1| COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Methanosarcina barkeri]
match: ----YDII-IIGTGTAGRTFAGKVAH------SGLKIAIVD---SR--------EYGGTCPI-RGCDPKEVL----TNITKV-I-DSSNRL-MGKGVRIDA-P--LKLDWTSLIKF-KKTFTEGYSS---KTEKHLVGM--GIDTYHG-RAH-F-ENQNTV-----VVGMDKLK-G-----------------------EH-I-FLATGAKPR--TL----NIPG--E---EYI----I--TSE--KLME-T-K-K-L-PE-K-I-----IFIGGGYISMEFA-HI-ARR---TGAEVTILQRSE-KV--L-RAFDSD-M--V-DLLM-KASKAAGIKI---L-TNKPVISV-EKD-NN-G-LI-LK-V-----QSQ-SETEPEIQIFRADMVVQGAGRVADIEDLR--LENARIK-TEK--G-AIV-VDKHM--RT--S---NSRIYA--GGDCA-----------------------------LEG-----MQLTPVAALQG-EVA---A-INVLEGDS---A--EADY--TGI-PSAVFTIPVLASVGISVAKDDDK-Y---KV-IFQD---RSNWYT-----TRKKG-MEFAASKVI-IDEANDRIM-GAHILGPNA--EEAI-NIFASVMRLGL--KASDIKKLIFTYPTTCSDIPY-M--------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 6.4378E-84
12  >gi|2791905|emb|CAA73495.1| ORF454 [Staphylococcus sciuri]
match: ---KFDVV-FIGSG----HAAWHAA-L-TLKHAGKSVAIIE-----------KDTIAGTCTN-YGC-NAKILLEG-P--YE-VLEE--ASH-YP---QIIE-SDQLHVNWENLMQY-KKAVINPLS----NTLKSMFEQ-QGIEVIMGA-GK-L-VDAH-------TIDV---E-GTP------------------IQADN-I-VIATGQHSN--KL----DIEG--SA-LTH--------DSR--DFLS-L---DKM-PN-N-I-----TFIGAGIISIEFA-SIAIKS----GAEVHVIHHTD-K--PL-EGFNEKHI--A-KLIH-K-LESEGVQF--HF--NENVQSVQQA-----G-N-SYN-V---TTESG-LSIDT-------EYVLDATGRKPNVQNIG--LDELGIEYSEK--G--IR-VDDHL--RT--N---IHNIYA--SGD-------------------------------VLDKTIPK--LTPTATFES-NYI---A-SHILGINP---N--PIQY--PAI-PSVLYSLPRLSQIGVTVKEA------EDN-EAYTIKDI-PFGKQM---VFEYKN-EIEAEMTII-LNAD-KQLV-GAEIYADDA--ANLI-NLLTFIVNQKL--TAKDLNQLIFAFPGSSSGVLD-L--------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.54637E-83
13  >gi|30248843|ref|NP_840913.1| merA; mercuric reductase [Nitrosomonas europaea ATCC 19718] >gnl|BL_ORD_ID|803871 merA; mercuric reductase [Nitrosomonas europaea ATCC 19718]
match: ------VA-VIG--SGG--AAM-AAAL-KAVEQGAKVTLIE-----------RGTIGGTCVN-VGCVPSKIMIRA-AHIAH--LRRESPFD-GGIPATAP------AIDRSKLLAQ-QQARVDELRHAKYEGI--LDGN-PAITVLHGE-AR-F-KDDQSL-----VVRL-NAG-GERVVVF-----------------DR-C-LVATGASP---AVP---PIPG--LK--ESP----Y-WTST--EAL--V-S-DII-PE-R-L-----AVIGSSVVALELA-QA-FAR---LGSQVTILARST-LF--F-RE-DPA-I--G-EAIT-AAFRAEGIKV---L-EHTQASQV--AH-VD-G---EF--V-LTTAR-G----EIH-----ADKLLVATGRTPNTRSLA--LEAAGVAV-NA-QG-AIV-IDKGM--RT--S---APHIYAA--GDC-------------------------------TD----QPQFVYVAAAAG-TRA---A-INMTGGD----A--TLDL--TAM-PAVVFTDPQVATVGYSEAEA-----HHDGIET-DSRTLT-LD-NVPRALANFDT-RGFI--KLV-IEEGSGRLI-GVQAVAPEA--GELI-QTAALAIRNRM--TAQELADQLFPYLTMVEGL------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.86745E-82
14  >gi|22124238|ref|NP_667661.1| putative oxidoreductase [Yersinia pestis KIM] >gnl|BL_ORD_ID|1063114 putative oxidoreductase [Yersinia pestis KIM]
match: -----------------------------LVKQGARVAVIERY----------NNVGGGCTH-WGTIPSKALRHAVSRIIE--FNQ---NPLYS-----DN-ARTIKSSFADILNH-ADRVINQ-QTRMRQG---FYDR-NHCHMFSGD-AS-F-IDAN-------TVNVRYAD-GTSD----------------TLQADN-I-VIATGSRPY--R-P--VNVD---FN-HE----R-I-YDSD--TILQ-L-S-HE--PQ-H-V-----IIYGAGVIGCEYA-SI-FRG---LSVKVDLINTRD-RL--L-AFLDQE-M--S-DALS-YHFWNNGVVIRH----NEEFEQI-EGT-TD-G----VI-VHL---KSG-KKVK-------ADCLLYANGRTGNTSGLG--LENIGLE-ADS-RG-LLK-VNSMY--QTALS-----HVYAV--GD-------------------------------VIGY----PSLASAAYDQGRIA----A-QAMIKGE----ANVHL---IEDI-PTGIYTIPEISSVGKTEQELTAM---KVPYEVGRA-QFKHL----ARAQIVGMD-TGSL--KIL-FHRETKQIL-GIHCFGERA--AEIIHIGQAIMEQKGEGNTLEYFVNTTFNYPTMAEAY------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.88755E-81
15  >gi|23055499|ref|ZP_00081599.1| COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Geobacter metallireducens]
match: ----HDLV-ILGSGSTAFAAALRAQSY------GTRVLMVEKGVP-----------GGTCIN-WGCVPSKTLIHA-ALFYQE-GK-LGAR--LGLG---EC-GGTVVLE--RLMAR-KDQVVGHLRQT--KYLDILQDV-PGLQLVKGT-GR-F-LGPDR-------LEV-----GDREI-----------------RSER-F-LVAVGGDP---RVP---RIPG--LE-STPF----L--TSR--GTLL-L-K-T-I-PQ-S-L-----VIIGGGVIAVEMG-QM-FQR---LGAKVTILEHGP-RI--L-GPVEPE-P--A-LAVR-DFLRAEGMKIVCR-------TTICLAA-QD-G-AG-VR-V-----EAE-R--DGERVSFTAEKLLVATGTAPATNGIG--LELAGVE-TDP-RG-FVT-VDERM--RT--T---APGIWAA--GDC-------------------------------TG----GMMIATVGAREG-IVA---V-DDML--NPGCGC--SMDFLSA---PMAIFTDPEVGMVGHTEEGAKAA--GFD-VVV----NVMPV-AAIPKAHVTGHT-AGVI--KMV-ADKATGRLL-GVHLACHRG--ADIINEA-ALAIRFRA--TVEDLANALHVYPSMGE---G-LR-------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 9.68744E-79
16  >gi|27467283|ref|NP_763920.1| mercuric reductase-like protein [Staphylococcus epidermidis ATCC 12228] >gnl|BL_ORD_ID|538514 mercuric reductase-like protein [Staphylococcus epidermidis ATCC 12228]
match: ---NYDLI-IIGFGKAGKTLAAHAAG------HGQKVAVVE--QSTK-------MYGGTCIN-IGCIPTKTL-----------IHD-------GIEGN--------SFKES--ITR-KKEVVQALNNKNYQG---LNSK-NNIDVLN-YNAK-F-ISNE-------IIELQDSN-GTIQ-------ETIT--------ADK-I-LINTGSRA---NIP---DIKG--ID-TAQN----I-YDST--GLLN-I---DYQ-PQ-E-L-----VIIGGGYIALEFA-SM-FAN---FGTHVTILERGD-AI--M-TNEDQD-I--A-NLIV-KDLQDKGVTI------NTNTSTI--AF-SN-N-KDQ-T-I-IHT-NHG----EIS-----ADTVLLATGRKPNTNHLG--LENTDVKI-GK-QGEVI--VNKHL--QS--T---VKHIYAA--GD-------------------------------VKG----GLQFTYISLDDY-RII---K-SHLFGDGS---R--TTE-NRGAI-PYTVFIDPPLSRVGLIASEA-KL-QGYD---ILDNKVFVS---NIPRHKINNDS-RGLF--KAV-INKDTKEIL-GASLYGKES--EELI-NLIKLAIDQHI--PYTVLRDNIYTHPTMTESFND-LFLE-----------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.34354E-76
17  >gi|28870285|ref|NP_792904.1| glutathione reductase [Pseudomonas syringae pv. tomato str. DC3000] >gnl|BL_ORD_ID|618340 glutathione reductase [Pseudomonas syringae pv. tomato str. DC3000]
match: ----FDLF-VIGAGSGGVRAARFAAGF------GARVAVAE---SRY--------LGGTCVN-VGCVPKKLLVYG-AHFSED-F-D-HAK---GFGWSLG----EASFDWSTLIAN-KDREINRLNDI-YRKL--LVD--SGVTLLEG-HAK-I-V-GPQ------QVEI---N-GQTH----------S--------AER-I-LIATGGWP---QVP---DVPG---R--EHA----I--TSN--EAFY-L-K-A-L-PK-R-V-----VVVGGGYIAVEFA-SI-FNG---LGADTTLVYRGE-LF--L-RGFDGS-V--R-SHLH-EELLKRHMTI--RF--NSDIERI-DKQ-SD-G-S--L--L-L-SMKGG-GTLET-------DCVFYATGRRPMLDNLG--LDSVDVKL-DE-HG-YIK-VDEHY--QT--S---EPSILAL--GD---V---------------------------I-G----GVQLTPVALAEG-MAV---A-RRLFKPEQY--R--PVDY--NHI-PTAVFSLPNIGTVGLTEEDAIKA--GHD-VQVFES-RFRSMKLTL----TDDQE-RTLM--KLV-VDAKTDRVL-GCHMVGPDA--GEIV-QSLAIAIKAGA--TKQVFDDTIGVHPTAAEEFVT-MR-------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 4.25544E-71
18  >gi|6714837|gb|AAF26175.1| glutathione reductase [Glycine max]
match: ----FDRF-TIGAGSGGVRARRFAANY------GASVAICELPFSTISSE-TTGGVGGTCVI-RGCVPKKLLVYA-SKFSHE-FEE--SN---GFGWRYDS---EPKHDWSSLIAN-KNAELQRLTGI-YKNI--LNN--AGVKLIEG-HGK-I-IDPH-------TVDV---N-GK--L--------YS--------AKH-I-LVTVGGRP---FIP---DIPG---N--EYA----I--DSD--AALD-L-P-T-K-PE-K-I-----AIVGGGYIALEFA-GI-FNG---LKSEVHVFIRQK-KV--L-RGFDEE-I--R-DFVS-EQMSVRG--I--EFHTEESPQAI-TKS-AD-G-S--FS-L-K-TNKG---TVDG------FSHIMFATGRRPNTQNLG--LESVGVKIAKD--G-AIE-VDEYS--QT--S---VPSIWAV--GD---V----------------------------TN----RINLTPVALMEG-GAL---V-KTLFQDNPT--K--P-DY--RAV-PSAVFSQPPIGQVGLTEEQAVQQ-YG--DIDIFTA-NFRPLKATL----SGLPD-RVFM--KLV-VCAKTNEVL-GLHMCGDDA--PEIV-QGFAVALKARL--TKADFDATVGIHPSAAEEFVT-MR-------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 5.41454E-71
19  >gi|37522440|ref|NP_925817.1| unknown protein [Gloeobacter violaceus] >gnl|BL_ORD_ID|337631 glr2871 [Gloeobacter violaceus PCC 7421]
match: ---KADVI-VIGSGQGGVPLAVDQAR------SGRRVVLFE-----------RGALGGSCIN-YGCTPSKALLAA-AHAAGR-AR--LAAP-LGIHAEV-------TVDFARVMER-VRGIRASFRQG-IEQ--RLAD--AGVQIVHAE-AS-F-AGSS-------TV-V---G-GGVEV-----------------QAPL-V-VINTGTGP---TIP---ELPG--LA-GLPL----L--TNL--NIFD-L---ETL-PR-C-T-----LILGGGYIGLEL--G---QGLARLGSEVHIVHNHE-RL--L-NHEEPE-V--G-EVLA-EALRRDGIHL--HLQSEVS-QAVYQ----D-G-ICALT-L-----EDG-QILRGE------AALLAAAGRTPNTAALG--APAAGIAL-DK-QG-YVA-IDEHF--RT--T---AAGVYAI--GD-------------------------------VAR----QPAFTHVSWEDY-RRL-----QAILGGEE--RT--RSD---RVL-GYAVYTEPQVGRVGLTLDQALAK--GHRARSV----TL-PMAH-IARAIEWGHD-LGFY--RLV-VDEDTDKIL-GATLVGYEA--AEIVHVLLA-HMQADS--TWKVLEQSVHIHPTYCEALPS-LARLLK---------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.89677E-70
20  >gi|6650836|gb|AAF22039.1| glutathione reductase [Candida albicans]
match: ----FDYL-VIGGGSGGVASARRAAKY------GAKVLLIE---SNFKK------FGGTCVN-VGCVPKKVMWYT-ADLAHK-KHDLYA---YGLDKEPES-IKYGDFDWAKLKHK-RDAYVTRLNGI-YENN--LKR--EKVDYAYG-FAK-F-INS-EG-----EVEVTL-S-GDQELPFLDEGKTYKKGEKLVFSADM-T-LIATGGTA---IVPP--SVPG---A--ELG----T--TSD--GFFA-L-E-K-Q-PK-K-V-----AIVGAGYIGVELS-GV-FSS---LGSETHFFIRGD-TV--L-RSFDEV-I--Q-NTVT-DYYID---NLGINIHKQSTITKI-EGS-KD-G-K---K-V-V-HLKDG-TSVE------V-DELIWTVGRKSLID-IG--LDKVGVKINDK-Q--QIV-ADEYQ--VT--N---NPKIFSL--GD-------------------------------VVG----KVELTPVAIAA----V---S-SIDIVSD-C--K--IMDI---HI-HQCILT-SRAG-LWFITREPLKI-RG-GNLKYIIL-NLSPMYYAM-------------M---MI---KKINHLS-STRSFVSDP--EE------KV-IKMGA--TKKDFDNCVAIHPTSAEELVT-M--------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.3264E-59
21  >gi|29833890|ref|NP_828524.1| putative oxidoreductase [Streptomyces avermitilis MA-4680] >gnl|BL_ORD_ID|912722 putative oxidoreductase [Streptomyces avermitilis MA-4680]
match: --IAYDVV-VLGAGPVGENVADRTRA------AGLSTAVVE-----------SELVGGECSY-WACMPSKALLRPV-------IARADARRVPGVS----H-LAQGHLDTAAVLAH-RDYEVSHWKDD--GQVGWL-DG-IGADLYRG-HGR-LS-GPR-------EVTVTGPD-GDRRV----------------LTARHAV-AVCTGSRAL---LP---DLPGLD-Q-VEP-------WTSR--EA----TS-AQAAPG-R-L-----IVVGGGVVAVEMATA--WRA---LGSEVTVLVRGK-GL--LPR-MEP--F--AGELVA-EALKEAGADVR----TGTSVSAVTRE-----G-PT----VVVLT-DTG-DRIE-------ADEILFATGRAPRTDDLG--LDTVGLE-----PGSWLS-VDDSL--RVTGS----DWLYAV--GDV-------------------------NHRALLTHQGKYQARIAGAAIAA--RAS--GV--PLLESDPWGAHAATADH--AAV-PQVVFTDPEAAAVGLSLAEA-ER-AGH-HVRAVDV-EFS----SVAGAGLYADGYRG--RARMV-VDVNRETLL-GVTFVGPGV--GELIHSA-TIAV-AG-EVPIGRLWHAVPSYPTISEVWLR-L--------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.90855E-56
22  >gi|18309716|ref|NP_561650.1| NADH oxidase [Clostridium perfringens] >gnl|BL_ORD_ID|797086 NADH oxidase [Clostridium perfringens str. 13]
match: --MSKKIV-IVGGVAGG---ASTAARLRR-LDENNQIIMFER-------G-PHVSFSN-C-----CLP--YYLSGKVENHEDLV--LMTPEKF---------YSQYRID-ARVYT----EVVS------------INRKAKEVTVRN--------------------V-V---S-GQE----------------YTESYDK-L-VLSPGAKAI---VP---PIKG--IEDVNVFTVRNV-V--DIAK-LDSFIK-D---NNSKNIS-----VIGGGFIGVEVAENLHEA-----GYNVTLIEAMD-QI--M-KPFDYDMV----QVLH-KEMYDKGVN----LIVGDKVSSF------ESG---KV--V----LESG-KKIN-------SDAVVMAIGVAPETD-LA---REAGLEIGQ--TG-AIK-VNQNY--LTNDK-----DIYAV--GDAVEV-YNS-----------------------LTN-SISRLPLAGPAQKQA-RAV---A-DHI-HGRPSRNSGY---IGSSCVQ---IF-HYNGASTGLTEGQIKAM-NLSLNYDVVRV---------IPQDKVGLMPGSEPLHFKLI-FEVPTGRIL-GAQAIGKGN--ADKRVDIIATLIKMGG--TVEDLKDL-----------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 5.71897E-55
23  >gi|15672768|ref|NP_266942.1| NADH oxidase [Lactococcus lactis subsp. lactis] >gnl|BL_ORD_ID|17729 NADH oxidase noxC [imported] - Lactococcus lactis subsp. lactis (strain IL1403) >gnl|BL_ORD_ID|17729 NADH oxidase [Lactococcus lactis subsp. lactis]
match: --MTEKIL-IVGGVAGGMSAATRLRRL----NENAEIIVFEK---------------GPYVSFANC---------------------------GLPYYVGG---EIA-EREKLIVQSAKALKNRFN------LE-VREN-SEVIAIDSEGKK-V------------TV-V--SN-GES-----------------YVESYDKL-ILSPGAKPL---IP---QIKGLN-QATNVFSLRNI---PDVDKIMTYLKA-KA--PKSA-------TIIGAGFIGLEMAENLA-KR----GLSVTIVEKAP-HV--L-PTIDRE-M--A--AFVNEELIKNNLSV---M---TNRGAVEFKN-DE---------ILL---DNG-ESLQ-------SDLTILSVGIQPET-SLA---KSAGIKLG--LRN-AIL-VDEHY--ET--S---VKDIYAV--GDAIVV-KNQ------------------------LGQDAL-ISLASPANRQGRQV----A-D-IISGLPIKNRGS----LGTAIVR--VF-DLQVASTGLSEFQLRGL-KINHKIVHVTANNHAGYYPDVTS-----------IVLKLI-FEPESGQIF-GAQAIGKEG--VDKRIDILSTAIKAKL--TVFDL--------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.59045E-49
24  >gi|24379549|ref|NP_721504.1| NADH oxidase (H2O-forming) [Streptococcus mutans UA159] >gnl|BL_ORD_ID|9051 NADH oxidase (H2O-forming) (EC 1.6.-.-) - Streptococcus mutans >gnl|BL_ORD_ID|9051 H2O-forming NADH Oxidase [Streptococcus mutans] >gnl|BL_ORD_ID|9051 NADH oxidase (H2O-forming) [Streptococcus mutans UA159] >gnl|BL_ORD_ID|9051 H2O-forming NADH oxidase
match: -----------------------------------------------------------------------------------------------------------------IG--KQ--ISGPQGLFYADKESLEAKGAKI-YMESPVTA-IDYDAKRV-----TALV---N-GQEH-----------------VESYEKL-ILATGSTPI---LP---PIKGAAIKEGSRDFEATL-KNLQFVKL----------------------AVVGAGYIGVELAEA--FKR---LGKEVILIDVVD-T--CLAGYYDQD-L--S-EMMR-QNLEDHGIEL--AF--GETVKAI-------EG-DGKVERIV--TDKASHD----------VDMVILAVGFRPNT-ALG----NAKLK-TFR-NGAFL--VDKKQ--ET--S---IPDVYAI--GDCATV-YDNA----------------------INDTNY--IALASNALRSG---I--VA-GHNAAGHKL--ESLGVQ-GSNGI---SIFGLNMVST-GLTQEKA-KR-FGYNP-EV---TAFTDFQKA---SFIEHDNYP--VTLKIV-YDKDSRLVL-GAQMASKED--MSMGIHMFSLAIQEKV--TIERLALL-----------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 7.8686E-48
25  >gi|14520939|ref|NP_126414.1| thioredoxin reductase [Pyrococcus abyssi] >gnl|BL_ORD_ID|145595 thioredoxin reductase (trxb) PAB0500 - Pyrococcus abyssi  (strain Orsay) >gnl|BL_ORD_ID|145595 trxB thioredoxin reductase [Pyrococcus abyssi]
match: ---VWDVI-IIGAGPAGYTAAIYAARF------GLDTIII------------TKDLGG---N-MA-ITD--LIENYPGFPE------------GISG-------------SELAKR-MYEHVKKY------GVDVIFD---EVVRIDPAECA-YYEGP-------CQFEVKTAN-GKEY-------------------KGKTI-IIAVGAEPRKLHVPGEKEFTGRGVS---YCA------TCD--GPL--FV-------G-KEV-----IVVGGGNTALQEA--LYLHS---IGVKVTLVHRRD-KF----RA-D--------KILQ-DRLKQAGIPTI--L--NTVVTEIR-------G-TNKVESVVLKNVKTG-ETFEKK-----VDGVFIFIGYEPKTD-F---VKHLGI--TDE-YG-YIK-VDMYM--RTK-----VPGIFAA--GD-------------------------------ITN--VFK-QIA-VAVGQGAIAA--NS-AK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 4.42837E-45
26  >gi|10120656|pdb|1F6M|A Chain A, Crystal Structure Of A Complex Between Thioredoxin Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+ >gnl|BL_ORD_ID|613738 Chain B, Crystal Structure Of A Complex Between Thioredoxin Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+ >gnl|BL_ORD_ID|613738 Chain E, Crystal Structure Of A Complex Between Thioredoxin Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+ >gnl|BL_ORD_ID|613738 Chain F, Crystal Structure Of A Complex Between Thioredoxin Reductase, Thioredoxin, And The Nadp+ Analog, Aadp+
match: ------LL-ILGSGPAGYTAAVYAAR------ANLQPVLI------------------TGME-KGGQ-----LTTTTEV-ENWPGD--PNDLTG----------------PLLMER-MHEHATKFETEII-----FDHI-NKVDLQNR---P-FRLNGD--------------N-GE-----------------YTCDA---L-IIATGASARYLGLPSEEAFKGRGVS-ASA--------TCD--GFFY---------RN-QKV-----AVIGGGNTAVEEA--LYLSN---IASEVHLIHRRD--------GFRAEKI--LIKRLM-DKV-ENG-NII--LHTNRTLEEV--TG-DQMG----VTGVRLRDTQNS-DNIESLDVAG----LFVAIGHSPNT-AI---FEG-QLEL--E-NG-YIK-VQSGI--HGNATQTSIPGVFAA--GD-------------------------------VMDH-IYRQAITS-AGTGCMAAL--DA-ERYLDGLADA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.36917E-44
27  >gi|15616133|ref|NP_244438.1| thioredoxin reductase (NADPH) [Bacillus halodurans] >gnl|BL_ORD_ID|638307 thioredoxin reductase (NADPH) trxB [imported] - Bacillus halodurans (strain C-125) >gnl|BL_ORD_ID|638307 thioredoxin reductase (NADPH) [Bacillus halodurans]
match: ---VYDVV-IAGAGPAGMTAAVYTSR------ANLSTVMVER---------------G--------VPGGQM--ANTEDVE---------NYPGFDHILG---PELS---TKMFEHAK-----KF------GAEYAYGDIKEI-IDQGDL-K-L-------------VK----A-GNKE-----------------YKARA-V-IVATGAEYKKLGVPGEKELSG-----------RGVSYCAVCDGAF--F--------KGKEL-----VVVGGGDSAVEEA--VYLTR---FASKVTIIHRRD-QL----R---------AQKILQQRAFDNDKIEFIW----DHVVKQI--NG-TD-G---KVSSVTIEHAKTGEQQ-D-----FKTDGVFIYIGMLPLNEAVK-NLN---I-LNDE--G-YIV-TNEEM--ET--S---VPGIFAA--GD-------------------------------VREKSL-RQIVT--ATGDGSLAAQ-NV-QHYIEELAEK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.671E-39
28  >gi|18450326|ref|NP_569197.1| pli0044 [Listeria innocua] >gnl|BL_ORD_ID|983475 pli0044 [Listeria innocua]
match: ----MKYV-IVGTSHAGF----EAVQTLLKKDSDAEIVVFE---------------AGSTASFLSC---------------------------GIQ--------------SYL-----EDISKSLDELHYANEASYKE--QGVD-IRMNTSV-IAINPET-----KEITTRTTD-GVEA----------------TESYDK-L-LLSPGG------VPG--TIPNVDDQHENIFYLRG----RNWADKV----K-NRMSSAKKAV------VVGAGYIGIEAA--IAYAQ---AGIDVTVVDFVD-SI--LPTYLDSEFT--S---LLTKHMEEKGMKIK----TGEGVKEFKVNE-NN-----EVTAVV---TDKG--TYE-------ADTVIISVGVRPNTQ----WLKDT-LTL--DGRG-FVE-VNEHM--ET--S---VKDVYAA--GDATAI-PFAP-----------------------TNDKAY-IALATNARRQGVIMAR-HA-----SGDADA-KIGRVN-GTSGL---AVF-DYKFATTGIKDANANSY-QGNVK-SVYKEDLIRP---SF-----MHDEEKVLM--KL-HYDADNGRIL-GAQLMSTY----DILQAINAVSVAIEAEWTVDQLAQ------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.92181E-38
29  >gi|34849459|gb|AAP58958.1| dihydrolipoamide dehydrogensae [Spiroplasma kunkelii]
match: -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIKNKVKIETSV----KIKVI--K-----G-----KTV-VYDNSDG-KEVKL-----TSDYCLVSVGQTPVTTCF----ENIGLKIWER-KN--IE-VDEQC--KT--N---LPGVYAI--GN-------------------------------VVGCT----MLAHVDSVQG--IL--VI-DSI-KGKNV-----KMNY--NRI-PSCIYSFPEVATVGITEEQAIKA-----KIA-YKAFKF--LLSANGKAIAYGET-DGFV--KILC-DPKYGEIL-GVHIVAATA--TDMIY-GITACMETEG--TIHELAKTVHPYPIL----------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.27181E-37
30  >gi|15903366|ref|NP_358916.1| NADH oxidase [Streptococcus pneumoniae R6] >gnl|BL_ORD_ID|129575 NADH oxidase (EC 1.6.-.-) [imported] - Streptococcus pneumoniae (strain R6) >gnl|BL_ORD_ID|129575 NADH oxidase [Streptococcus pneumoniae R6]
match: --------------------------------------------------------------------------------------------------------------------WIGEQIDGAEGLFYSDKEKLEAKGAKV-YMNSPVLS-IDYDAK--------V-VTAEVEGKEHK-----------------ESYEKL-IFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSD------KSQHL--DRIAVVGGGYIGVELAEA--FER---LGKEVVLVDIVD-TV--LNGYYDKDF-----TQMMAKNLEDHNIRL--AL--GQTVKAI-------EG-DGKVERL-ITDKES----FD-------VDMVILAVGFRPNTA-----LADGKIELFRN--GAFL--VDKKQ--ET--S---IPGVYAV--GDCATV-YDN------------------------ARKDTSYIALASNAVRTGIVGAY-NACGHELEG-------IGVQ-GSNGI---SIYGLHMVST-GLTLEKA-KA-AGYNATET----GFNDLQKP---EFMKHDNHE--VAIKIV-FDKDSREIL-GAQMVSHDIAIS-MGIHMFSLAIQEHV--TIDKLALT-----------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.79012E-35
31  >gi|21230307|ref|NP_636224.1| alkyl hydroperoxide reductase subunit F [Xanthomonas campestris pv. campestris str. ATCC 33913] >gnl|BL_ORD_ID|600053 alkyl hydroperoxide reductase subunit F [Xanthomonas campestris pv. campestris str. ATCC 33913]
match: ----FDVL-VVGGGPAGSAAAVYAAR------KGIRTGVA------------AERFGGQVLD--------TM---------------SIENFISVP----------ETEGPKMAAAL-EQHVRQYD----------------VDIMNLQRAE-QLIPAGA----DGLVEIKLAN-GAS------------------LKSKT-V-ILSTGARWRQMNVPGEDQYRN-----------KGVAYCPHCDGPL--F--------KGKRV-----AVIGGGNSGVEAA--IDLAG---IVAHVTLVEFDD-KL----RA-DE--V--LQRKL--RSLHN--VRII----TSAQTTEVL-------GDGQKVTGLVYKDRTGG----DTQHID--LEGVFVQIGLLPNTE-F---LRGT-VELSP--RGEII--VDDRG--QTN-----VPGVFAA--GDATTV-PYKQIVIAMGEGSKAALSAF---DYLIRSSAPVSADVAQAA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.01448E-34
32  >gi|17559934|ref|NP_505112.1| nfrl (60.3 kD) (5I678) [Caenorhabditis elegans] >gnl|BL_ORD_ID|666605 Hypothetical protein F20D6.11 [Caenorhabditis elegans]
match: ---------------------------------------------------------------------------------------------------------------RL--R-KDDAF--YEE---RNVKFLLKT--SV----------IAVNHKS-----REVSL--SN-GET-----------------VVYSK--L-IIATGGN-----V-RKLQVPGSDLK--NICYLRKV-EEAN---IISNL------HPG-KHV-----VCVGSSFIGMEVASALAEKA-----ASVTVI--SN-TPEPL-PVFGSD-I--G-KGIR-LKFEEKGVKF--EL--AANV--VALRG-NDQG---EVSKVIL---ENG-KELD-------VDLLVCGIGVTPATK-F---LEGSGIKL-DN-RG-FIE-VDEKF--RTNISY-----IFAM--GDVVT------------------------APLPLWDIDSINIQHFQTAQAHGQHLG--Y---TIV-GKPQPGPI--VPYFW-----TLFF----FA-FGL--KFSGCN-QGSTK----------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 4.33737E-34
33  >gi|11253045|pir||T43405 probable dihydrolipoamide dehydrogenase (EC 1.8.1.4) - fission yeast (Schizosaccharomyces pombe) >gnl|BL_ORD_ID|171585 dihydrolipoamide dehydrogenase [Schizosaccharomyces pombe]
match: ----YDLC-VIGGGPGGYVAAIRGAQL------GLKTICVE----------KRGTLGGTCLN-VGCIPSKALLNN-SHIYHT-VKHDTKRR--GIDVS------GVSVNLSQMMKA-KDDSVKSLT----SGIEYLFKK-NKVEYAKGT-GS-F-IDPQ-------TLSVKGID-GAAD---------------QTIKAKN-F-IIATGSEVK--PFPG-VTIDE--KK---------I-VSST--GGPY-L-Y-QRY-PK-K-M-----TVLGGGIIGLEMG-SV-WSR---LGAEVTVVEFLP-AVG---GPMDAD-I--S-KALS-RIISKQGIKFKR----STKL--VSAKV-N--G--DSVE-VEIENMKNN-KR-ETYQT----DVLLVAIGRVPYTEGLG--LDKLGISM-DK-SNRVI--MDSEY--RT--N---IPHIRVI--GDAT-----------------------------L------GPMLAHKAEDEG-IAA---V-EYIAKGQ----G--HVNY--NCI-PAVMYTHPEVAWVGITEQKAKES--G---IK-YRIGTF-GFSAN-SRAKTNMDA-DGLV--KVI-VDAETDRLL-GVHMIGPMA--GELIGEA-TLALEYGA--SAEDVARVCHAHPTLSE--------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.15216E-30
34  >gi|16131244|ref|NP_417824.1| nitrite reductase (NAD(P)H) subunit [Escherichia coli K12] >gnl|BL_ORD_ID|34518 Nitrite reductase [NAD(P)H] large subunit >gnl|BL_ORD_ID|34518 nitrite reductase [NAD(P)H] (EC 1.7.1.4) - Escherichia coli  (strain K-12) >gnl|BL_ORD_ID|34518 NADH-nitrate oxidoreductase apoprotein [Escherichia coli] >gnl|BL_ORD_ID|34518 nitrite reductase (NAD(P)H) subunit [Escherichia coli K12]
match: ---------------------------------------------------------------------------------DLLDKSDAAN-FDITV-FCE-EPRIAYDRVHLSSYFSHHTAEELS--LVR--EGFYEK-HGIKVLVGERA--ITINRQE--------KVIHSSAGR------------------TVFYDK-L-IMATGSYPW---IP---PIKGS--DTQDCFVYRTI-------EDLNAI---ESCARRSKR-----GAVVGGGLLGLEAAGA--LKN---LGIETHVIEFAP-ML--MAEQLDQ--M--GGEQLR-RKIESMGVRV----HTSKNTLEIV-----QEG----VEARKTMRFADG-SELE-------VDFIVFSTGIRPR-DKLA---TQCGLDVAP--RGGIV--INDSC--QT--SD---PDIYAI--GECASW-NNR-----------------------VFGLVAPGYKMAQVAVDH---ILG-S--ENAFEGADLSAKLKLL-----GV---------DVGGIG----DA----HGRTP----GARSYVYL-----------DESKE-IYKRLI-VSEDNKTLL-GAVLVGDTSDYGNLL-QLVLNAIEL-----------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 7.52353E-30
35  >gi|37675842|ref|NP_936238.1| putative oxidoreductase [Vibrio vulnificus YJ016] >gnl|BL_ORD_ID|995597 putative oxidoreductase [Vibrio vulnificus YJ016]
match: -MMSDPII-IIGS---GF-AAYQ---------------LV-----------------------------KSVRRLDAHI---PIQIFTADD--GAEYN--------KPDLSHVFSK-RQTAAD-L---VVKSGEAFA-TEHNVQL----HAH-TQVE--RVLTQQQQV-V--AN-GRCYPY-----------------SK--L-VFATGAQAF---VP---PMRGDGLAK--------V-MTLNSLQEYQA-AE-QPL-SRAQHV-----LVIGGGLIGVEIA--LDLATS---GKQVTVVEPNA-RL--LANLL-PEFI--ALP-LE-QQLMKHGIQL--AL--NSRVESVTVQ-----G-Q-TLA-IAL---HDG-REF-------AVDAVLCAAGLKANT-AVA---REAGLSV--E-RG--IC-VDLQL--NT--SD---PHIYAL--GDCAQ----------------------------IEGRML--PYLQPIVLSANVLA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.21666E-29
36  >gi|15425686|dbj|BAB64316.1| lipoamide dehydrogenase [Arthrobacter globiformis]
match: ----FDIL-VLGGGSGGYAAALRAVQL------GLTVGLVE-----------KGKLGGTCLH-NGCIPTKALLHS-AELADH-ARD--SAK-YGVNVTLD------SIDINAVNAY-KDGIIA---GK-YKGLQGLIKS-KGITVIEGE-GK-L-QGTDTV-----VVNGTAYK-GKN------------------------I-VLATGSYSR--TLPG-LEIGG--K-----V----I--TSD--QALT-M---DYI-PK-S-A-----IILGGGVIGVEFA-SV-WKS---FGVDVTIVEGLP-SL--V-PNEDAT-I--V-KNFE-RAFKKRGIKFSTGVF----FQGV-EQN-DD-G----VK-V---TLVDG-KTFEA-------DLLLVAVGRGPVTANLG--YEEAGITI-DR--G-FVI-TNERL--HT--G---VGNVYAV--GD---I---------------------------VPG-----VQLAHRGYQQG-IFV---A-EEIAGLKPV--V--VEDI---NI-PKVTYSEPEIATVGYTEKAAKEK-FGEDQVQ--TQ-EYN-L--AGNGKSSILGT-SGLV--KLVR-QKD-GPVV-GVHMIGARM--GEQVGEA-QLIVNWEA--YPEDVAQLLHAHPTQNE--------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 4.4563E-29
37  >gi|24373856|ref|NP_717899.1| thioredoxin reductase [Shewanella oneidensis MR-1] >gnl|BL_ORD_ID|822078 thioredoxin reductase [Shewanella oneidensis MR-1]
match: -----NLL-ILGSGPAGYTAAVYAAR------ANLKPVMI------------------TGMQ-QGGQ-----LTTTTEV-ENWPGD--AEDLTG----------------PALMER-MQKHAEKFDT------EILFDHINEVTLTER---P-F--------------RLKGDN-GE-----------------YTCDA---L-IIATGASARYLGLESEEAFKGRGVS-ACA--------TCD--GFFY---------RN-QKV-----AVIGGGNTAVEEA--LYLSN---IAAEVHLIHRRD--------TFRSEKI--LIDRLM-DKV-ANG-NIILHL--NQTMDEVVGDA---MG----VTGLKMKSTKDG-AITDLA-----VAGVFVAIGHSPNT-GI---FEG-QLEM--N-NG-YLK-VQSGL--QGNATQTSIEGVFAA--GD-------------------------------VMDQH-YRQAITS-AGTGCMAAL--DA-ERYLDAKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.65059E-28
38  >gi|25010186|ref|NP_734581.1| Unknown [Streptococcus agalactiae NEM316] >gnl|BL_ORD_ID|261181 Unknown [Streptococcus agalactiae NEM316]
match: ----YDVI-VLGFGKAGKTLAAKLAT------QGKSVAMVE--------E-DDKMYGGTCIN-IGCIPTKTLLVSASK----------------------------NHDFQEAMTT-RNEVTSRLRA---KNFAMLDNK-DTVDVYNAK-AR-F-ISNK-------VVELT--G-GADK---------------QELTAD-VI-IINTGAKSV--QLP----IPGL-AD-SQH-----V-YDST--AIQE-L-A-H-L-PK-R-L-----GIIGGGNIGLEFA-TL-YSE---LGSKVTVIDSQS-RI--FAR--EEEEL--S-EMAQ-DYLEEMGISF--KL--SADIKSVQNED-ED------VV-ISF---ED-----EKL----SFDAVLYATGRKPNTEGLA--LENTDIKLTE--RG-AIA-VDEYC--QT--S---VENIFAV--GD-------------------------------VNG----GPQFTYISLDDSRIVL------NYLNGD----KDYSLK-NRGAV-PTSTFTNPPLATVGLDEKTAKEK--G---YQV-KSNSL--LVSAMPRAHVNNDL-RGIF--KVV-VDTETNLIL-GARLFGAES--HELI-NIITMAMDNKIPYTY--FQKQIFTHPTMVENF------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.48262E-26
39  >gi|32037653|ref|ZP_00135925.1| COG0492: Thioredoxin reductase [Pseudomonas aeruginosa UCBPP-PA14]
match: ------LI-ILGSGPAGYTAAVYAAR------ANLKPVVI------------------TGIQ-----PGGQL-TTTTEV------DNWPGDVEGLTG-------------PALMTR-MQQHAERFDT------EIVYD---HIHT-----AE-LQQRP---------FTLKGDS-GT-----------------YTCDA---L-IIATGASAQYLGMSSEEAFMGKGVSA-----------CATCDGFFY----------RNQVV-----CVVGGGNTAVEEA--LYLAN---IAKEVHLIHRRD-KL-------RSEKI--LQDKLFDKA--ENG-NV--RLHWNTTLDEVLGDA-S--G----VTGVRLKSTIDG-STSEL-----SLAGVFIAIGHKPNTD-L---FQG-QLEMRD---G-YLR-IHGGS--EGNATQTSIEGVFAA--GD-------------------------------VADH-VYRQAITS-AGAGCMAAL--DA-EKYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.1763E-26
40  >gi|19746953|ref|NP_608089.1| putative NADH oxidase/alkyl hydroperoxidase reductase [Streptococcus pyogenes MGAS8232] >gnl|BL_ORD_ID|781283 putative NADH oxidase/alkyl hydroperoxidase reductase [Streptococcus pyogenes MGAS8232]
match: ---LYDVL-VIGGGPAGNSAAIYAAR------KGLKTGLL------------AETFGGQVMETVG-I-EN-MI--------------------G----------TLYTEGPKLMAE-VEAHTKSYD----------------VDIIKAQLAT--SIEKKE------NIEVTLAN-GA------------------VLQAKTAI-L-ALGAK--WRNI----NVPG----EDEFRNKGVT-YCPHCDGPL--F--------EGKDV-----AVIGGGNSGLEAA--LDLAG---LAKHVYVLE-----F--L-PELKADKV------LQ-DR-AADTANM-------TIIKNVATKD-I-VG-DDHVTGLNYTERDSG----EDKHLD--LEGVFVQIGLVPNT---A-WLKDSGVNLTD--RGEII--VDKHG--STN-----IPGIFAA--GDCTDS-AYKQIIISMGSGATAAIGAF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.13554E-25
41  >gi|15808973|gb|AAL08575.1| thioredoxin reductase [Mycobacterium avium subsp. paratuberculosis]
match: ---VHDVI-IIGSGPAGYTAALYTAR------AQLAPVVFE-----------GTSFGG------------ALMTT-TEV----------ENYPGFRDGITG---------PELMDQMREQAL-RF------GADLRMEDVESVSL-AGPVKS-----------------VTTAE-GE------------------TVRARA-V-ILAMGAAARYLGVPGEQDLLG-----------RGVSSCATCDGFF--F--------KDQDI-----AVIGGGDSAMEEAT--FLTR---FARSVTLVHRRE-EF----R---------ASRIMLERARANDKITIV----TNKAVEAV-------EG-SETVTGLRLRDTVTG----ETSTL--AVTGVFVAIGHDPRSE-L---VRDV-LD-TD-PDG-YVL-VQGR---TTATS---IPGVFAA--GD-------------------------------LVDRT-YRQAVT--AAGSGCAAAI-DAERWL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.32147E-20
42  >gi|6320560|ref|NP_010640.1| Thioredoxin reductase; Trr1p [Saccharomyces cerevisiae] >gnl|BL_ORD_ID|187939 Thioredoxin reductase 1 >gnl|BL_ORD_ID|187939 thioredoxin-disulfide reductase (EC 1.8.1.9) TRR1 [validated] - yeast (Saccharomyces cerevisiae) >gnl|BL_ORD_ID|187939 Similar to Thioredoxin reductase (Swiss Prot. accession numbers P09625 and Q05741), Alkyl hydroperoxide reductase F52A protein (Swiss Prot. accession number P19480), NADH Dehydrogenase (Swiss Prot. accession number P26829), and other pyridine nucleotide-disulphide oxidoreductase class-II FAD-containing flavoproteins. [Saccharomyces cerevisiae]
match: -MVHNKVT-IIGSGPAAHTAAIYLAR------AEIKPILYE----------------GMMAN--G-IAAGGQLTTTTEI----------ENFPGFPDGLTG---------SELMDRMREQS-TKF------GTEIITETVSKVDLSSKPF-K-LWTEFN-------------ED-AEP------------------VTTDA-I-ILATGASAKRMHLP------G-----EETYWQKGISACAVCDGAVPIF--------RNKPL-----AVIGGGDSACEEAQ--FLTK---YGSKVFMLVRKD-HL----R---------ASTIMQKRAEKNEKIEI---LY-NT-V-ALEAK-----G-DGKL--LNALRIKNTKKNEET---DLPVSGLFYAIGHTPATKIV------AG-QVDTDEAG-YIKTVPGSS--LT--S---VPGFFAA--GD-------------------------------VQDSK-YRQAITS-AGSGCMAAL--DA-EKYLTSLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.23065E-16
43  >gi|21220950|ref|NP_626729.1| putative nitrite reductase large subunit NirB [Streptomyces coelicolor A3(2)] >gnl|BL_ORD_ID|1075320 putative nitrite reductase large subunit NirB [Streptomyces coelicolor A3(2)]
match: ---------------------------------------------------------------------------------------------------------------------------------------FIAE-HGIELRVGDPAE--TIDREAR-------RVTARS-G------------------LVVEYD-VL-VLATGSYPF---VP---PVPG---KDAEGCF---V-Y-RTIEDLLA--IE-AYARTRATTG-----AVVGGGLLGLEAAGA--LNG---LGLTSHIVEFAP-RL--MPVQVDEGGG--A--ALL-RTIEEMGLSVHTGV--GTQ--EI-TTG-ED-G-A--VTGMKL---SDG-SELAT-------DLVVFSAGVRPR-DQLA---RDCGLAVGER-GG--IS-VDERC--RTVTDE----RVFAI--GECALA-AD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 5.24769E-10
44  >gi|396309|gb|AAC43068.1| unknown dehydrogenase A
match: -------------------------------KQGARVAVIERYQ----------NVGGGCTH-WGTIPSK-LRHAVSRIIE--FNQ---NPLYSDHSRL------LRSSFADILNH-ADNVINQ-QTRMRQG---FYER-NHCEILQGN-AR-F-VDEH-------TLALDCPD-GSVE----------------TLTAEK-F-VIACGSRPY--H-PT--DV--------DFTHPR-I-YDSD--SILS-M-H-HE--PR-H-V-----LIYGAGVIGCEYA-SI-FRG---MDVKVDLINTRD-RL--L-AFLDQE-M--S-DSLS-YHFWNSGVVIRH----NEEYEKI--EG-CDDG-------V-IMHLKSG-KKLK-------ADCLLYANGRTGNTDSLA--LQNIGLE-TDS-RGQ-LK-VNSMY--QTAQ-----PHVYAV--GD-------------------------------VIGY----PSLASAAYDQGRIA----A-QALVKGE-------ATAHLIEDI-PTGIYTIPEISSVGKTEQQLTAM---KVPYEVGRA-QFKHL----ARAQIVGMN-VGTL--KIL-FHRETKEIL-GIHCFGERA--AEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAY------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 9.26028E-10
45  >gi|19703527|ref|NP_603089.1| Sarcosine oxidase alpha subunit [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] >gnl|BL_ORD_ID|534040 Sarcosine oxidase alpha subunit [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]
match: --IKYDLV-IVGGGPAGLAAAVEARKNRID-----NILVIE----------RAKELGGI-LQQ--CIHNGFGLH---EFKEELTGPEYAQRF------MDQ-LFELNIEY-KL-----DTMV--L------GI-----SENKI--VQA-------INS---------V-----D-G-----------------YMIIQAKS-V-ILTMGCR---ERTRGAIAIPGDRPAG--------I-FTAGAAQRYINMEG-YMV---GKRV-----VILGSGDIGLIMARRLTLE-----GAKVLAV---A-ELMPFSGGLTRNIV---------QCLDDYDIPL---YLSHTVVDII--------G-KDRVEKVIIAKVDENKKAIHGTEIEYECDTLLLSVGLIPE-NDIS---RATGIKIDPR-TNGPI--VNELM--ET--S---IVGIFA--SGNVVHV-HDLVDFVSIESRKAGK-----SAAKYIKGE---------VA--DGEYI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.51548E-6
46  >gi|15925390|ref|NP_372924.1| nitrite reductase [Staphylococcus aureus subsp. aureus Mu50] >gnl|BL_ORD_ID|442432 nitrite reductase [Staphylococcus aureus subsp. aureus Mu50]
match: ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-IFATGSKAFV--IP----VPGSTLP-SVIGWRT-I-DDTE--QMMN-IAK-T----K-KKA-----IVIGGGLLGLECARGL-LDQ----GMEVTVLHLAE-WLMEM--QLDRK----AGNMLK-ADLEKQGMKF--EM--QANTTEIL-------G-EDDVEGVKL---ADG-REI-------PADLVVMAVGIRPYTE-VA--KES-GLDV--N-RG--IV-VNDVM--QTSDS-----NVYAV--GEC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 1.10402E-5
47  >gi|30261358|ref|NP_843735.1| pyridine nucleotide-disulfide oxidoreductase, class I [Bacillus anthracis str. Ames] >gnl|BL_ORD_ID|91597 pyridine nucleotide-disulfide oxidoreductase, class I [Bacillus anthracis str. Ames]
match: ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-LIATGVRPV---MP---EWEGRDLQ-GVHLLKT-I-PDAE--RILKTLET-NKVED----V-----TIIGGGAIGLEMAET--F---VELGKKVRMIERND-HIGTI---YDGD-M--A-EYIY-KEADKHHIEI---L-TNENVKAF--K-----G-NERVEAV---ETDKG-T--------YKADLVLVSVGVKPNTD-F---LEGTNIR-TNH-KG-AIE-VNAYM--QT--N---VQDVYAA--GDC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 2.95592E-4
48  >gi|20809045|ref|NP_624216.1| uncharacterized NAD(FAD)-dependent dehydrogenases [Thermoanaerobacter tengcongensis] >gnl|BL_ORD_ID|164821 uncharacterized NAD(FAD)-dependent dehydrogenases [Thermoanaerobacter tengcongensis]
match: ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-LIGTGSTAI---VP---PWEGRNLPG--VFTLKTM-GDAE--KLLDWLSS-HT--PT-KAV------VIGGGYIGLETAEALH-SR----GFKVTVLDLAP-Q---LIPTFDKE-I--A--EIAQDALTRHGVEV--HL--NEEV--VGLEG-DEKG----VKAVV---TKNG--KFE-------ADLVIISIGVRPVSE-LA---KEAGIELGPK-N--AIL-VNERL--ET--S---IPDIYAA--GDC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

Blast e-value: 3.24006E-4
49  >gi|23016561|ref|ZP_00056315.1| COG1251: NAD(P)H-nitrite reductase [Magnetospirillum magnetotacticum]
match: ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-LLATGSKPLMPPLPG-LDLPGV-VAFRD------I---ADVEKMLDA--A-E----KQQRA-----VVIGGGLLGLEAAWG--LKRR---GMPVALVHLMP-TL--MERQLDVE----AGGLLQ-KDLTERGLHF---F-TSGQTEEIM--G-AEEG-CA--KGVKL---TDG-REI-------PADLVVVAIGIRPNVD-LA---KAAGLDI--N-RG--IE-VGDDM--AT--SD---PAIFSV--GEC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
query: --MVYDLI-VIGGGSGGMAAARRAARH------NAKVALVE--KSR---------LGGTCVN-VGCVPKKIMFNA-ASVHDI-LEN--SRH-YGFDTKF-------SFNLPLLVER-RDKYIQRLNNI-YRQN--LSK--DKVDLYEG-TAS-F-LSENRI-----LIKGTKDN-NNKDN------GPLNEE---ILEGRN-I-LIAVGNKP---VFP---PVKG---I--ENT----I--SSD--EFFN-I-K-E---SK-K-I-----GIVGSGYIAVELI-NV-IKR---LGIDSYIFARGN-RI--L-RKFDES-V--I-NVLE-NDMKKN--NI--NIVTFADVVEI-KKV-SD-K-N--LS-I----------HLSDGRIYEHFDHVIYCVGRSPDTENLK--LEKLNVE-TNN-N--YIV-VDENQ--RT--S---VNNIYAV--GDCCMV-KKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNVQLTPVAINAG-RLL---A-DRLFLKKT---R--KTNY--KLI-PTVIFSHPPIGTIGLSEEAAIQI-YGKENVKIYES-KFTNLFFSVYDIEPELKE-KTYL--KLVCVGKD-ELIK-GLHIIGLNA--DEIV-QGFAVALKMNA--TKKDFDETIPIHPTAAEEFLT-LQPWMK---------------------------------------------

                        

3D Structures:
Click below to view the 3D structure of a PDB homolog related to your protein.
  • 1ONFA (e-value = 0.0) - Matches to residues 2 - 641
  • 1GERA (e-value = 5.0E-97) - Matches to residues 3 - 641
  • 1BWCA (e-value = 5.0E-95) - Matches to residues 3 - 641
  • 1ZDLA (e-value = 4.0E-71) - Matches to residues 3 - 640
  • 1AOGA (e-value = 2.0E-66) - Matches to residues 2 - 641
  • 1H6VA (e-value = 8.0E-66) - Matches to residues 3 - 640
  • 1FEAA (e-value = 5.0E-62) - Matches to residues 3 - 641
  • 3LADA (e-value = 1.0E-44) - Matches to residues 3 - 635
  • 1LPFA (e-value = 7.0E-43) - Matches to residues 3 - 635
  • 1EBDA (e-value = 8.0E-42) - Matches to residues 4 - 635
  • 1JEHA (e-value = 6.0E-37) - Matches to residues 3 - 637
  • 1DXLA (e-value = 7.0E-36) - Matches to residues 4 - 635
  • 1ZMCA (e-value = 2.0E-32) - Matches to residues 4 - 637
  • 2A8XA (e-value = 1.0E-30) - Matches to residues 3 - 633
  • 1ZK7A (e-value = 9.0E-30) - Matches to residues 7 - 628
  • 1XDIA (e-value = 6.0E-18) - Matches to residues 5 - 632